Pioglitazone (Actos) Reactions Please

A board to discuss future MS therapies in early stage (Phase I or II) trials.

Pioglitazone (Actos) Reactions Please

Postby amelia » Mon Jul 24, 2006 1:01 pm

I have a friend that is interested in Pioglitazone (Actos). I saw it listed in the Phase 2 trials. I looked it up, but don't trust just any site on research stats. Anybody hear anything about it, on it, etc? I'd love to hear some input.
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Actos

Postby lyndacarol » Mon Jul 24, 2006 7:04 pm

I am the website's resident believer that excess insulin production is involved in MS. Because Actos reduces circulating insulin levels (according to the Physicians' Desk Reference) I asked my doctor if I could try it. He agreed, but I saw no change in MS symptoms from my two-month trial. I did develop swelling of the ankles and feet (a published possible side effect), which took quite a long time to absolve.

Actos made no difference for me, but I still believe insulin plays a role.
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