ElliotB wrote:According to this article, a company from France called INSERM has successfully tested a drug with mice that seems to prevent MS disease progression.
FranceInfo wrote:Researcher at INSERM, Fabien Docagne is one of the authors of this discovery: "This is a key and lock system that exists at this wall and that will allow these cells to move within the brain. We also found a drug that will be capable of blocking this lock and will thus prevent cells from going inside the brain, and therefore, to attack our nerve cells. " He added that "this drug has shown significant efficacy in mice, a mouse that has something that resembles multiple sclerosis. When we give this drug, the mouse is better. It prevents disease progression and mice have no paralysis of the rear axle. this treatment has shown no side effects in mice. in these circumstances, given its effectiveness, it is hoped that one day this target may become a treatment in humans. "
Despite the vast array of mouse models EAE is the most frequently exploited paradigm used to develop therapeutic approaches. However, despite over one thousand compounds used in the treatment of EAE few have become licenced for treatment of MS so far.
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