MBP8298

A board to discuss future MS therapies in early stage (Phase I or II) trials.

MBP8298

Postby bromley » Thu Sep 07, 2006 9:48 am

BioMS Medical expands pivotal multiple sclerosis trial into Spain and Germany

BioMS Medical Corp, a leading developer in the treatment of multiple sclerosis (MS), today announced it has received approval from the Spanish Agency for Medicines and Healthcare Products (SAMHP) in Spain and from the Federal Institute for Medicines and Medical Products in Germany to start patient enrolment for its pivotal phase II/III clinical trial of MBP8298, a proprietary synthetic peptide for the treatment of secondary progressive multiple sclerosis (SPMS).
Pivotal Phase II/III Multiple Sclerosis Trial

BioMS Medical is currently enrolling patients across Canada, the U.K., Sweden, Denmark and The Netherlands in its pivotal phase II/III clinical trial evaluating MBP8298 for the treatment of secondary progressive multiple sclerosis (SPMS). The trial is a randomised, double-blind study enrolling approximately 553 patients who will be administered either MBP8298 or placebo intravenously every six months for a period of two years. The primary clinical endpoint for the trial is defined as a statistically and clinically significant increase in the time to progression of the disease as measured by the Expanded Disability Status Scale (EDSS), in patients with HLA-DR2 and/or HLA-DR4 immune response genes. Time to disease progression in patients with other HLA-DR types will be assessed separately as an exploratory arm of the same study. To date the trial has successfully passed five safety reviews by its independent Data Safety Monitoring Board.

Source: BioMS Medical Corp.
User avatar
bromley
Family Elder
 
Posts: 1889
Joined: Fri Sep 10, 2004 3:00 pm

Advertisement

sounds good

Postby gwa » Thu Sep 07, 2006 10:51 am

This sounds good. I will look forward to the trial results.

gwa
User avatar
gwa
Family Elder
 
Posts: 846
Joined: Thu Dec 01, 2005 4:00 pm


Return to Drug Pipeline

 


  • Related topics
    Replies
    Views
    Last post
  • MBP8298
    by dignan » Wed May 03, 2006 7:52 am
    5 Replies
    2591 Views
    Last post by dignan View the latest post
    Thu Jun 22, 2006 8:24 am
  • MBP8298
    by bromley » Thu Oct 12, 2006 11:39 am
    0 Replies
    1022 Views
    Last post by bromley View the latest post
    Thu Oct 12, 2006 11:39 am
  • MBP8298
    by dignan » Thu Apr 05, 2007 1:30 pm
    0 Replies
    1128 Views
    Last post by dignan View the latest post
    Thu Apr 05, 2007 1:30 pm
  • MBP8298
    by dignan » Tue Jun 05, 2007 2:20 pm
    0 Replies
    1313 Views
    Last post by dignan View the latest post
    Tue Jun 05, 2007 2:20 pm
  • Update on MBP8298
    by bromley » Wed Feb 08, 2006 3:39 am
    0 Replies
    1343 Views
    Last post by bromley View the latest post
    Wed Feb 08, 2006 3:39 am

Who is online

Users browsing this forum: No registered users