This Is MS Multiple Sclerosis Community: Knowledge & Support

I have a question about Tovaxin since I am thinking about participating in the clinical trial. I have seen that some people here are participating in the clinical trial and must have had a chance to have their questions answered. I don't know much about the immune system and I was wondering if it was possible in theory for the Tovaxin vaccine to not only destroy myelin reactive T-cell but to destroy all T-cell in the immune system. I know it never happened before. But in theory, could this happen?

Hi Jessr,

I'm also trying to get into that trial. That sounds like a question for your doctor? I would think it is pretty safe since they only use your blood. The previous trials have had a very good safety record, even though they were small.

_________________
Take care, Ewizabeth Previously Avonex, Rebif & Copaxone RRMS ~Tysabri, 31 infusions, ended 9/09. Starting Copaxone 12/09, waiting for Cladribine to be approved in 2010.

I am not in any trial, or have any medical training.

I would feel safe in this trial because,
1) They create a vaccine specific to your autoreactive T-Cells. I would guess in doing this they would test it before injecting that it would not kill ALL T-Cells.

2) The fact that you have to get another treatment would leave me with the impression that if it did go wrong, it would also fade.

3) You will be monitoured, I would hope with many a blood test after your first injection.

Personally, my biggest fear would be the placebo.

Good Luck Jessr!

Thanks Cure and Ewizabeth

00

Bob,
Sort of like the flu shot I guess, is why it needs repeating. I'm sure it's way far over my head.

_________________
Take care, Ewizabeth Previously Avonex, Rebif & Copaxone RRMS ~Tysabri, 31 infusions, ended 9/09. Starting Copaxone 12/09, waiting for Cladribine to be approved in 2010.

00

Me too Bob. My appointment to sign up is Friday. Thankfully I have been relentlessly busy all weekend and will be this week too. I'm not very good at being patient, but I think I should learn, and fast!

_________________
Take care, Ewizabeth Previously Avonex, Rebif & Copaxone RRMS ~Tysabri, 31 infusions, ended 9/09. Starting Copaxone 12/09, waiting for Cladribine to be approved in 2010.

00

I already watched those Bob... they are really good videos! I hope they are accurate representations of what we will get from this treatment! (says Ewizabeth, the old lady college student )

_________________
Take care, Ewizabeth Previously Avonex, Rebif & Copaxone RRMS ~Tysabri, 31 infusions, ended 9/09. Starting Copaxone 12/09, waiting for Cladribine to be approved in 2010.