Clinical trial results

A board to discuss future MS therapies in early stage (Phase I or II) trials.

Clinical trial results

Postby dignan » Sun Apr 01, 2007 10:00 am

Sharon recently mentioned that the AAN meeting abstracts are available for viewing online, but there is an embargo on them until the day they are presented. There are several abstracts reporting clinical trial results or preliminary results, a few that caught my eye are:

-- Minocycline + Copaxone (finally!)
-- Rituxan for RRMS
-- Atorvastatin (Lipitor) + Rebif (finally!)
-- Campath

The link to the abstracts: http://www.abstracts2view.com/aan2007boston/
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Postby carolew » Sun Apr 01, 2007 10:42 am

I can't find the abstract for the combo of Lipitor and Rebif. Do you remember under which topic it was listed? thanks Carole
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Postby dignan » Sun Apr 01, 2007 3:12 pm

It's from this session:

Wednesday, May 2 - Scientific Sessions: Multiple Sclerosis: Clinical Trials III (3:45 PM-5:00 PM)
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Postby carolew » Mon Apr 02, 2007 4:04 am

Thanks Dignan, I got it. A bit disappointing, I must admit. Carole
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Re: Clinical trial results

Postby NHE » Mon Apr 02, 2007 4:43 pm

carolew wrote:A bit disappointing, I must admit. Carole

This abstract might provide an explanation.
[S59.005] Statins Block Interferon Signaling in Human Immune Cells: Potential Loss of the Therapeutic Effect of IFN-β in Multiple Sclerosis - 04:45 PM

NHE
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Postby CureOrBust » Tue Apr 03, 2007 3:00 am

not from any scientific standpoint, but i think the rebif was blocking the statins in my case. Just a single persons experience.
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Postby carolew » Wed Apr 04, 2007 4:24 am

That came to my mind as well. Carole
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