Estriol

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Estriol

Postby dignan » Wed Jan 23, 2008 8:10 am

I hadn't heard about this...



FDA Launches Misguided Attack on Estriol, Despite Proof it is Safe and Effective for Women, says Dr. Erika

"Why would the FDA try to take estriol off the market when it is not only safe for women in menopause, it may even help women with multiple sclerosis," writes Dr Erika. Maybe it is because the agency is more concerned with protecting Wyeth than it is with protecting women, she says. Wyeth is the manufacturer of the top-selling synthetic hormone replacement therapies on the market. Earlier this month, the FDA sent warning letters to compounding pharmacies over the effectiveness of the bioidentical hormones prescribed by an increasing number of physicians. The agency also warned it is considering a ban on estriol. The FDA action was in response to a so-called "citizen's petition" sponsored by Wyeth.

PRWEB - January 23, 2008 - The Food and Drug Administration has launched a misguided attack on estriol despite overwhelming evidence it is safe and effective for women in menopause, according to Erika Schwartz MD at www.DrErika.com.

"Why would the FDA try to take estriol off the market when it is not only safe for women in menopause, it may even help women with multiple sclerosis," writes Dr. Erika. Maybe it is because the agency is more concerned with protecting Wyeth than it is with protecting women, she says.

Why would the FDA try to take estriol off the market when it is not only safe for women in menopause, it may even help women with multiple sclerosis.

Wyeth is the manufacturer of the top-selling synthetic hormone replacement therapies on the market. Earlier this month, the FDA sent warning letters to compounding pharmacies threatening a ban on estriol. The FDA said its action was in response to a "citizen's petition" voicing concern about compounded bioidentical hormones submitted by Wyeth to the FDA October 2005.

In her blog, Dr. Erika explains what estriol is, how it works and how it has been studied in this country and overseas since the 1980s.

She notes that Jonathan Wright MD, an American leader in the field of bioidentical hormone therapies, created a combination of estriol and estradiol known as Biest to treat symptoms of menopause. The success of this combination has translated in its extensive use by compounding pharmacies around the country for the past 10 years.

Most recently estriol has been studied in the treatment of multiple sclerosis in women. It is a scientifically supported and well known fact that women who suffer with autoimmune diseases like rheumatoid arthritis, thyroiditis and MS experience significant improvement in these conditions during pregnancy. Since estriol is the dominant estrogen during pregnancy, research is presently being conducted to evaluate estriol's effect on MS.

Doses of estriol similar to those circulating in the blood stream of a pregnant woman in the middle of her pregnancy (6-8 mg/day) have shown significant remission of the disease and hold much promise. Dr. Rhonda Voskuhl at UCLA has been conducting very important estriol studies on women with MS and the results are very promising.

In an article on NeurologyReviews.com in 2002 Dr. Voskuhl was quoted as saying estriol at pregnancy doses had been given in Europe and Asia in the form of hormone replacement therapy for symptoms of menopause, "which means we didn't have to reinvent the wheel on assessing toxicity. It was very well known how this estriol preparation would be tolerated. Therefore we could go straight to a phase I clinical trials focusing on multiple sclerosis-related disease measures."

Dr. Erika says: "No adverse reactions or long term negative side-effects have been reported with the use of estriol by physicians or patients using this bioidentical hormone to the FDA to my knowledge."

Thousands of women are discovering Dr Erika at www.DrErika.com. The site helps women become strong, smart and healthy through education, empowerment and kindness.

Dr. Schwartz, its founder, is dedicated to providing an honest view on health care topics and issues from a position of devoted patient advocacy.

Dr. Schwartz is an internationally-recognized patient advocate, practicing physician, expert in conventional and integrative medicine and a frequent guest on TV and radio. She has written four books, lectures on health and wellness issues and authored a magazine column read by more than 10 million people a week.

http://www.prweb.com/releases/2008/01/prweb645431.htm
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Estriol and the FDA

Postby Shayk » Fri Jan 25, 2008 5:13 pm

Dignan

I really appreciate your posting this even though it’s seriously grim news for me personally. I knew the FDA had sent out warning letters to 7 compounding pharmacies but once I confirmed the pharmacy I use wasn’t among them I went merrily on my way—so I missed this too. I thought the warning pertained to advertising and marketing and totally missed the specific restriction on estriol.

The pharmacies that received warning letters from the FDA are listed here.

I mentioned Wyeth’s petition almost two years ago in this thread. At the time it provided me with a wonderful opportunity to try and educate legislators and bureaucrats about the potential of hormones (bioidentical) to treat MS. Clearly that didn’t work.

If anyone is interested in contacting their legislators now, here’s a link that makes it really easy to do that. And, if you do contact your legislator(s), thanks in advance and please personalize your letter. Form letters get counted but that’s about it. Personal letters are taken far more seriously.

Thanks again Dignan--and everyone.

Sharon :( and :evil:
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Postby cheerleader » Thu Jan 31, 2008 9:29 am

Wow-
This is really not right...of course big pharma would be against a natural product that cannot be patented. I posted re: bioidentical hormones on another thread. Still learning, but the information is fascinating! Glad it's helping you, Sharon.


http://www.thisisms.com/ftopict-5058.html
best,
AC
Husband dx RRMS 3/07
dx dual jugular vein stenosis (CCSVI) 4/09
http://ccsviinms.blogspot.com
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Postby edife » Fri Oct 09, 2009 4:17 pm

http://video.cbs12.com/m/26842685/legal ... nefits.htm

My local news here in Florida had the above story on Wyeth yesterday.
They had insiders claim to be world known doctors hyping Prempro/Premarin. Class action sounds easy. Call firm.

FDA's site has the 2008 news headline stating Wyeth told them ESTRIOL is NG. Liars.

http://www.fda.gov/NewsEvents/Newsroom/ ... 116832.htm

GoodLuck. Yes I have MS and paraplegia and want estriol which was cheap!
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Postby edife » Mon Oct 12, 2009 9:26 am

The lawfirm phone # is 800 780 8607.
Ask if they'll be a class action against Wyeth and FDA since no proof was provided when FDA sided with Wyeth in Jan 2008.
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Postby edife » Wed Oct 14, 2009 1:54 pm

Or call FDA and ask if they could reconsider their decision after news came out October 2009 showing Wyeth lied and the consumer group is likely staff. Ask what the name of consumer group was.

news video link again : http://video.cbs12.com/m/26842685/legal ... nefits.htm
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FDA and Estriol

Postby Shayk » Wed Oct 14, 2009 6:24 pm

Hi Edife

I believe it's still possible to obtain a prescription that contains estriol.

Here's a link to some info and the FDA Application for an Investigational New Drug

I'm still taking estriol. You might want to think about contacting a compounding pharmacy and ask if any practitioners in your area have been approved to prescribe it.

Good luck.

Sharon
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Postby edife » Thu Oct 15, 2009 4:35 pm

Thankyou Sharon. Printed and ready for next neuro/med visit.
I had Estriol, Estrone, Estradiol, Progesterone, Testosterone levels run last week for baseline.
Once again they arent infront of me so I cant post #'s atm. Tomorrow tomorrow.
Estriol came back a tad out of range high which I find odd. I stopped Rebif 2 days prior which is made from http://en.wikipedia.org/wiki/Chinese_hamster_ovary_cell so maybe Rebif contains estrogens?
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