Progressive MS Pipeline

A board to discuss future MS therapies in early stage (Phase I or II) trials.

Re: Progressive MS Pipeline

Postby zen2010 » Sun Jan 24, 2016 11:05 am

dignan wrote:Upon request, here are the drugs from the pipeline that are being tested for progressive forms of MS. If I've missed anything, please let me know.



Progressive MS Treatment Pipeline - September 2011

Phase 3 Trials
- Gilenya (aka FTY720 and fingolimod) (PPMS) (Novartis)
- Masitinib (SPMS and PPMS) (aka Kinavet or AB1010) (AB Science)
- Ocrelizumab (R1594) (trial for PPMS) (Genentech, Roche, Biogen)
- Revimmune (aka high dose cyclophosphamide or cytoxan) (Accentia Biopharmaceuticals) (refractory MS - includes SPMS I think, not sure about PPMS)

Phase 2 Trials
- Amiloride (Oxford University) (PPMS)
- Fluoxetine (aka Prozac) (SP, PP & RRMS) (University Medical Center Groningen)
- GEM-SP (SPMS) (Gemacbio)
- Hydroxyurea (PPMS) (S. Andrea Hospital)
- Idebenone (National Institute of Neurological Disorders and Stroke)
- Lithium (US Department of Veterans Affairs)
- Mesenchymal Stem Cells (4 trials listed in clinicaltrials.gov)
- MIS416 (progressive MS) (Innate Therapeutics)
- PI-2301 (Peptimmune)
- Pixantrone (aka BBR 2778) (SPMS) (Cell Therapeutics)
- RTL1000 (Artielle ImmunoTherapeutics)
- Zocor (aka simvastatin) (SPMS) (MS-STAT trial - UK)


Hi all,

Can anyone pls update this status?

I tried to find something on the net but didn't get anything...

Thks
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Re: Progressive MS Pipeline

Postby zen2010 » Tue Jan 26, 2016 10:52 am

I found this interesting link below...
https://www.mssociety.org.uk/ms-researc ... peline#PMS
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Re: Progressive MS Pipeline

Postby UWE59 » Tue Aug 02, 2016 8:50 am

zen2010 wrote:I found this interesting link below...
https://www.mssociety.org.uk/ms-researc ... peline#PMS


This link is not available.
Kind regards UWE
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Re: Progressive MS Pipeline

Postby NHE » Tue Aug 02, 2016 8:54 pm

UWE59 wrote:
zen2010 wrote:I found this interesting link below...
https://www.mssociety.org.uk/ms-researc ... peline#PMS

This link is not available.

It works for me when I click on it.
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Re: Progressive MS Pipeline

Postby zen2010 » Wed Aug 10, 2016 11:37 pm

NHE wrote:
UWE59 wrote:
zen2010 wrote:I found this interesting link below...
https://www.mssociety.org.uk/ms-researc ... peline#PMS

This link is not available.

It works for me when I click on it.


Hi,

Forget about the previous link and try the one below:
http://www.nationalmssociety.org/Resear ... #section-0

BR
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Re: LIPOIC ACID AN OVER THE COUNTER ANTIOXIDANT, SEEN TO SLO

Postby seeva » Wed Jul 12, 2017 1:00 am

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