Statin and minocycline combo

A board to discuss future MS therapies in early stage (Phase I or II) trials.

Statin and minocycline combo

Postby bromley » Tue Mar 25, 2008 4:52 am

Those lucky mice are now getting a statin and minocycline combo.

Ian



<shortened url>
User avatar
bromley
Family Elder
 
Posts: 1887
Joined: Fri Sep 10, 2004 3:00 pm

Advertisement

Postby CureOrBust » Wed Mar 26, 2008 3:54 am

Our findings show that combined treatment, compared to using the medications alone, resulted in a significant reduction in disease severity, in both the acute and chronic phases of the disease, along with attenuation of inflammation, demyelination and axonal loss.

I am on both Lipitor and Mino. I have been worried that the combo may of been a no-no like Statins and Interferons. This mouse study raises my comfort level a little. Now to find out what happens in humans.
User avatar
CureOrBust
Family Elder
 
Posts: 2883
Joined: Wed Jul 27, 2005 3:00 pm
Location: Sydney, Australia

Postby carolew » Thu Mar 27, 2008 4:58 am

Do you know the dose of minocycline they are testing?
Or, perhaps, Cure, you could tell me what dose you are using. I am on the Lipitor too.
Thank you in advance, Carole
User avatar
carolew
Family Elder
 
Posts: 553
Joined: Fri Nov 05, 2004 4:00 pm
Location: Ottawa, Ont. Canada

Postby CureOrBust » Fri Mar 28, 2008 12:44 am

this one was a mouse study, and I dont remember that they give the mg/kg measurement either.

I am on 60-80mg of Lipitor (divided over 2-3 doses in the day), and 200mg/day (in a divided dose, ie 100mgx2) on minocycline.
User avatar
CureOrBust
Family Elder
 
Posts: 2883
Joined: Wed Jul 27, 2005 3:00 pm
Location: Sydney, Australia

Postby carolew » Fri Mar 28, 2008 4:04 am

thank you Cure... Carole
User avatar
carolew
Family Elder
 
Posts: 553
Joined: Fri Nov 05, 2004 4:00 pm
Location: Ottawa, Ont. Canada


Return to Drug Pipeline

 


  • Related topics
    Replies
    Views
    Last post

Who is online

Users browsing this forum: No registered users