Pipeline drug for re-myelination?

A board to discuss future MS therapies in early stage (Phase I or II) trials.

Postby DIM » Mon Jun 02, 2008 11:33 pm

Glyconutrients increase stem cell counts in the blood of
patients taking them for only one week more than 400x so it's a good alternative choice and if one believes Mannatech Ambrotose is expensive (it is) there are many alternatives, for example Kelp contains the five glyconutrients glucose, mannose, galactose, fucose, xylose Aloe Vera contains glucose, xylose, mannose Shark cartilage contains N-acetyl glucosamine and whey/egg protein contain N-acetyl neuraminic acid.
Unfortunately the last two glyconutrients can't be found easily in foods.
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Re: Pipeline drug for remyelination?

Postby NHE » Tue Jun 03, 2008 12:33 am

Hi DIM,
Glyconutrients increase stem cell counts in the blood of patients taking them for only one week more than 400x

It would be great if you could post a reference for the above quote.

Thanks, NHE
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Postby DIM » Tue Jun 03, 2008 2:04 am

Read Dr Bob's article about glyconutrients in this magazine:
http://www.msrc.co.uk/downloads/npwm_2006_0035.pdf
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Postby DIM » Tue Jun 03, 2008 2:52 am

Ambrotose alternative in completely natural form:
http://www.evenbetternow.com/als-glyconutrients.asp
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Postby gwa » Tue Jun 03, 2008 8:25 am

DIM wrote:Read Dr Bob's article about glyconutrients in this magazine:
http://www.msrc.co.uk/downloads/npwm_2006_0035.pdf


Dr Bob is simply stating his "facts" without referencing any studies that would support his claims.

He has posted a long list of foods that contain all of these magical sugars and it looks to me like most people eating a healthy diet would already be incorporating most of these sugars. If not, then one would find it much cheaper to eat more of the foods listed and forget the pills.

He does refer to lawsuits and Mannatose, which are written about online. Bottom line is buy the pills if you want and see if you lose symptoms or cash faster.

gwa
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Postby DIM » Tue Jun 03, 2008 8:35 am

I don't suggest you to take glyconutrients just wonder about their effectiveness, although you can buy kelp extract and shark cartilage that give you 7 of the 8 glyconutreints with no needs for extra pills that cost!
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Postby gwa » Tue Jun 03, 2008 9:11 am

DIM wrote:I don't suggest you to take glyconutrients just wonder about their effectiveness, although you can buy kelp extract and shark cartilage that give you 7 of the 8 glyconutreints with no needs for extra pills that cost!


It would be rare to find a study that suggests for people to take supplements in lieu of food for getting nutrient requirements. If you look at postings by people pushing these pills, it is obvious that they have not been around long here and will probably disappear once they have pushed the Ambrotose miracles.

The list of foods shown containing the sugars are everyday foods that most of us would have been eating for years. Those on a diet of candy bars and cake snacks could probably benefit by looking over the foods listed on Dr Bob's site prior to spending money on glyconutrients.

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Postby DIM » Wed Jun 04, 2008 3:37 pm

It seems Chinese traditional herb can do the trick, very interesting article:
http://www.itmonline.org/arts/msalsmg.htm
Another interesting site:
http://content.nhiondemand.com/shp/HC3. ... 0&cType=hc
...it mentions why methyl-B12 is more important than B12, why the need for high doses D3, calcium-magnesium-zinc defficiencies, why MSers need only omega-3 supplementation, about herbs etc
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Postby gibbledygook » Fri Jun 13, 2008 4:11 am

Smilingface!
I'm soon to start the ren shen yang rong tang formula in tea format. My chinese doctor was very excited when I pulled out the pubmed research as the formula is very similar to one which his old professor used for MS patients, years ago. How are you finding yours?
3 years antibiotics, 06/09 bilateral jug stents at C1, 05/11 ballooning of both jug valves, 07/12 stenting of renal vein, azygos & jug valve ballooning,
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Postby Lars » Sun Jun 22, 2008 8:08 am

If you don't already have this site, it's a good one to keep your eye on.

www.myelinrepair.org
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Postby rainer » Thu Jun 26, 2008 6:53 pm

Columbus, OH -- Lieutenant Governor Lee Fisher, Chair of the Ohio Third Frontier Commission, today announced that the Commission recommended nearly $23 million in funding through the Ohio Biomedical Research Commercialization Program for six Ohio projects that target research and development in areas including improved prosthetic limbs, better treatment of asthma and cystic fibrosis, and expanded programs for burn care and nerve repair. The awards are contingent upon State Controlling Board approval.

...

The Cleveland Clinic, in collaboration with Case Western Reserve University and the University of Toledo, was recommended for $3 million in funding to develop small molecules that can enhance repair of the brain in multiple sclerosis with the goal not only of delaying progression of disability but reversing it. The lead compounds will be chemically optimized to obtain compounds suitable for licensing by major pharmaceutical companies as drug candidates.

http://www.odod.state.oh.us/newsroom/releases/1934.asp
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