ATL/TV 1102

A board to discuss future MS therapies in early stage (Phase I or II) trials.

ATL/TV 1102

Postby bromley » Mon Jun 30, 2008 1:23 am

Dignan,

Please note the slight change in name for this drug and the expectation that it will be moving into Phase 3.

Ian

ATL/TV1102 reduces disease activity in multiple sclerosis patients 30 June 2008

Teva Pharmaceutical Industries Ltd. and Antisense Therapeutics Ltd. announced that anti-sense drug, ATL/TV1102, significantly reduced disease activity in patients with relapsing-remitting multiple sclerosis.

The companies noted that their Phase IIa study met its primary endpoint showing a significant reduction by 54.4% in cumulative number of new active lesions in patients taking ATL/TV1102, compared to placebo. In general, ATL/TV1102 was well tolerated.

Based on these encouraging results, Teva said it intends to conduct additional pre-clinical and clinical research before continuing to a Phase III study with ATL/TV1102.

Antisense Therapeutics has two drugs in development and two drugs in pre-clinical research. ATL/TV1102 (injection) is in the advanced stages of a Phase IIa trial as a potential treatment of multiple sclerosis. ATL/TV1102 (inhaled) is at the pre-clinical research stage as a potential treatment for asthma. ATL/TV1102 has been licensed to Teva.

Teva is responsible for funding and performing future development activities for ATL/TV1102.

Teva's decision to move forward with the development of ATL/TV1102 will earn a US$4 million milestone payment under the license agreement between Teva and Antisense Therapeutics.

Source: RTTNews © 2008 RTTNews 30 June 2008
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Postby dignan » Mon Jun 30, 2008 8:17 am

What the heck does this mean?
Based on these encouraging results, Teva said it intends to conduct additional pre-clinical and clinical research before continuing to a Phase III study with ATL/TV1102.


"Clinical research"? That means more phase 2 trials before phase 3?
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