I have been doing a very similar program for the last 6 months. Its called 5x5 stronglifts. Basically after a warm up you do 4 compound lifts (using multiple muscles) such as deadlift, squat, bench press, barbell row, shoulder press. You lift an extremely heavy weight for 5 sets of 5 reps. The intensity is extreme and I sweat like a beast. I did find evidence that extremely intense exercise ruptures the Blood Brain Barrier. However, like any bodybuilder knows you must "break" muscle cells so that they super-compensate and grow bigger and stronger. Much like the saying no pain no gain
This may work for the endothelium as well.
Ld2014, or anyone else, do you have a link to that download? it would be much appreciated...http://www.ncbi.nlm.nih.gov/pubmed/24194479
"...it appears that the BBB may be compromised following exercise, with the severity dependent on exercise intensity..."http://www.ncbi.nlm.nih.gov/pubmed/1650437
"...These results suggest that short-term Free Swimming increases BBB permeability in specific brain regions..."