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Hi Pepsi- Behavioral changes can occur depending on where the lesions are. I am more impatient than I used to be and get frustrated a lot more easily. Has your friend had a neuro-psych assay done? That would give her a benchmark as to where she is right now. I was having problems processing information and getting words out. After my own neuro-psych testing, I started seeing a speech therapist, which has helped immensely.
If she's depressed and/or acting out inappropriately, she made need a good psycho-therapist. This disease can bring out a lot of emotions that we're not equipped to deal with. It may help her cope with what sounds like a lot of changes she's had to make. Thankfully, she has a good friend like you looking out for her.
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