Genome study identifies three possible drug candidates...

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Genome study identifies three possible drug candidates...

Postby MSUK » Fri May 02, 2014 6:15 am

Genome study identifies three possible drug candidates for autoimmune diseases

New pharmaceuticals to fight autoimmune diseases, such as multiple sclerosis, rheumatoid arthritis and psoriasis, may be identified more effectively by adding genome analysis to standard drug screening, according to a new study by a research team led by UC San Francisco and Harvard researchers, in collaboration with Tempero and GlaxoSmithKlein.

In a study reported online April 17, 2014 in the journal Immunity, the scientists combined drug screening with state-of-the-art techniques for analyzing the genome, leading to three small molecules that improved symptoms in a mouse form of multiple sclerosis....... Read More - http://www.ms-uk.org/genetics
MS-UK - http://www.ms-uk.org/
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Re: Genome study identifies three possible drug candidates..

Postby CureOrBust » Fri May 02, 2014 7:31 pm

MSUK wrote:Genome study identifies three possible drug candidates for autoimmune diseases

... the scientists combined drug screening with state-of-the-art techniques for analyzing the genome, leading to three small molecules that improved symptoms in a mouse form of multiple sclerosis

I find it a little ironic that they use their study of the genome to find a cure for a mouse disease instead of trying to find the difference between it (ie EAE) and MS. ie is there something in the genome that could help explain why EAE treatments fail on a different species (ie humans) if EAE is a "form" of MS. Their words, not mine.
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