Nerve conduction velocity gene linked to multiple sclerosis

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Nerve conduction velocity gene linked to multiple sclerosis

Postby MSUK » Wed Aug 13, 2014 1:21 am

Evidence found in both human multiple sclerosis patients and experimental mouse models, according to research published in the American Journal of Pathology.

A new study published in The American Journal of Pathology identifies a novel gene that controls nerve conduction velocity. Investigators report that even minor reductions in conduction velocity may aggravate disease in multiple sclerosis (MS) patients and in mice bred for the MS-like condition experimental autoimmune encephalomyelitis (EAE)...... Read more- http://www.ms-uk.org/genetics
MS-UK - http://www.ms-uk.org/
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Re: Nerve conduction velocity gene linked to multiple sclero

Postby CureOrBust » Wed Aug 13, 2014 4:33 am

Scientists said S1PR2 could work by helping to make the blood-brain barrier, in charge of stopping potentially harmful substances from entering the brain and spinal fluid, more permeable.

A more permeable barrier could let attacking cells, which cause MS, into the central nervous system, the study said.

Understanding 'crucial'
Prof Robyn Klein, of the Washington University School of Medicine, said: "We were very excited to find the molecule, as we wanted to find a target for treatment that didn't involve targeting the immune cells.
...
She would be looking at taking her findings to clinical trials in the "next few years", she added.
Did I miss something? what exactly would she be taking to trial? they haven't created a chemical that affects / controls the gene they have identified.
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