Stem cells 'able to reverse symtoms of multiple sclerosis'

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Stem cells 'able to reverse symtoms of multiple sclerosis'

Postby scorpion » Fri Feb 19, 2010 5:47 pm

I am glad the MS Society is calling for controlled clinical trials. Fingers crossed.....


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Postby Lyon » Fri Feb 19, 2010 6:02 pm

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Postby harry1 » Fri Feb 19, 2010 6:02 pm

For those of us who have paralyses from this disease (10 years in my feet now) this is GREAT news and thanks so much for posting it Scorpion !!!
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Postby scorpion » Fri Feb 19, 2010 7:22 pm

No problem Harry1. You have reason to be hopeful. As I have said before my wife is involved with stem cell research and she has told me of studies that have not yet been released that have had similar success. I guess we can all be hopeful but until we have conclusive proof we need to keep it in perspective. I will try to share information my wife receives from other universities and from the NIH to keep everyone on here "ahead of the game". Please remember the reults I post here are very early results. Stem cell therapy seems very promising but until larger clinical trials are completed "guarded optimism" are the key words.
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Postby Frank » Fri Feb 19, 2010 9:26 pm

What kind of SCT do they refer to? It seems they refer to bone marrow cells one time and fat tissue cells the other time.
So are the improvements due to a reboot of the immune system (ASCT) or is it due to the proliferation potential of precursor cells?

--Frank
Treatment: Gilenya since 01/2011, CCSVI both IJV ballooned 09/2010, Tysabri stopped after 24 Infusions and positive JCV antibody test, after LDN, ABX Wheldon Regime for 1 year.
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Postby jay123 » Sat Feb 20, 2010 3:13 pm

This is great news. I am hoping my upcoming CCSVI procedure will stop the progression, then it will be time to start looking for the fixes!
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Postby mhawks1990 » Sat Feb 20, 2010 8:20 pm

I am in Costa Rica right now about to get stem cell treatments.
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Postby L » Sat Feb 20, 2010 8:37 pm

That's fantastic news!

I think that this is the paper:
http://www.translational-medicine.com/c ... 5#IDAXUAH2

Boris Minev, quoted in teh Telegraph article, is a co-author.

But no mention of the improvements, what I really wanted to read..

If it is the right trial, they used "Endometrial Regenerative Cells (ERC)" which "are a population of mesenchymal-like stem cells having pluripotent differentiation activity and ability to induce neoangiogenesis."

Hmm. They talk about four patients, the Telegraph talks about three. But the dates are right, Spring 2009. Very mysterious!
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Postby mhawks1990 » Sun Feb 21, 2010 12:20 pm

Mine are adipose cells from myself. I had this last year and it worked so well. I walked normal and had no symptoms for several months. But, I quit taking my medicine. So this time I am doing a trial on myself. Im going to continue my medicine, get the treatment and see if it last longer. I am very excited about it. I do think it is sad that in the USA you can get stem cells to improve your facial features but not to help those of us with MS. We do have to be our own advocates. And I just love this website where we can all share our experiences and things we have learned so we can help each other. :D
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Postby L » Sun Feb 21, 2010 9:47 pm

Here's another promiosing article:
http://www.hindu.com/seta/2010/02/04/st ... 061400.htm

Those Swedes. Man kann inte rope hej thuran man kann over beken. Or something like that. It's the only thing I can say in Swedish but it does seem vaguely appropriate..

Especially in light of this, an article which states that, in fact, induced pluripotent stem cells (adult cells, skin cells for example, made to behave like embryonic cells) aren't in fact that great:
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Postby harry1 » Mon Feb 22, 2010 6:37 am

scorpion wrote:No problem Harry1. You have reason to be hopeful. As I have said before my wife is involved with stem cell research and she has told me of studies that have not yet been released that have had similar success. I guess we can all be hopeful but until we have conclusive proof we need to keep it in perspective. I will try to share information my wife receives from other universities and from the NIH to keep everyone on here "ahead of the game". Please remember the reults I post here are very early results. Stem cell therapy seems very promising but until larger clinical trials are completed "guarded optimism" are the key words.


Again it all sounds really good Scorpion .... and i also read on one of the ALS forums about how the biotechs Brainstorm and Neuralstem have started phase-I trials for people with that awful disease as they've reported great success in SOD-1 mice in their lab studies and also Geron Corp has started phase-I trials for Spinal Cord Paralyses do to accidents i.e. car crashes, falls etc.. as they are working on the use of stem cells to override the scar tissue that forms when the spinal cord is severed.

So yes i'm optimistic as stem cell trials are now advancing in many neurological diseases (finally) and i do wish your wife all the success in her research about this technology.

harry
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