An article published Online First and in the April edition of The Lancet Neurology reports that add-on daclizumab treatment might reduce multiple sclerosis disease activity more than standard interferon beta treatment alone. The article is the work of Dr John W Rose, Neurovirology Research Laboratory, VA Medical Center, Salt Lake City, Utah and University of Utah, USA, and colleagues.
Daclizumab is a humanised monoclonal antibody. It is a genetically engineered antibody with a human structure and specific binding sites. Daclizumab has reduced multiple sclerosis disease activity in earlier non-randomised studies. The authors aimed in this new study to investigate whether daclizumab reduces disease activity in patients with active relapsing multiple sclerosis who are receiving standard interferon beta treatment.
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