The Weird History of Vaccine Adjuvants

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The Weird History of Vaccine Adjuvants

Postby fernando » Fri Mar 26, 2010 8:56 am

http://scienceblogs.com/neuronculture/2009/10/the_weird_history_of_vaccine_a.php

Interesting reading.

"Adjuvants have been whimsically called the dirty little secret of vaccines [4] in the scientific community. This dates from the early days of commercial vaccine manufacture, when significant variations in the effectiveness of different batches of the same vaccine were observed, correctly assumed to be due to contamination of the reaction vessels. However, it was soon found that more scrupulous attention to cleanliness actually seemed to reduce the effectiveness of the vaccines, and that the contaminants - "dirt" - actually enhanced the immune response."


They don't know how adjuvants work. I don't want to be called an anti vaccine person, but if they don't even know how it works, I presume they know less if those substance have deleterious, subtle or long term effects in our systems or not.

Autoimmunity caused by "adjuvants"? There is an interesting comment at the end of the article:

In regards to squalene, yes, the body does contain it naturally, the problem is, in a vaccine, you are introducing it directly into the bloodstream, initiating an immune response to something occuring naturally, which is exactly what happens in autoimmune diseases. Its not "frothing at the mouth" for nothing, this can potentially have serious consequences to the health of those receiving squalene in a vaccine. Its also important to note, it has not been approved by the FDA, yet is is in the newest vaccine. Autoimmune diseases are on the rise, if components in a vaccine are contributing to the problem, don't you think it important to research it? Especially since this article notes that something works, but science doesn't understand how/why?
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It's not so sinister, really

Postby ScutFarkus » Tue Mar 30, 2010 1:50 pm

hey don't know how adjuvants work. I don't want to be called an anti vaccine person, but if they don't even know how it works, I presume they know less if those substance have deleterious, subtle or long term effects in our systems or not.


That's not a correct presumption. Clinical trials and long-term patient outcomes are how we can know a lot about "deleterious, subtle or long term effects in our systems," even without understanding the mechanisms of action. It's possible, and indeed fairly common, to know if something works and what its side-effects are long before science fully understands how it works. One classic example of this is aspirin.

Regarding the interesting comment you quote, the very next comment puts it in perspective:
When is the last time you had a vaccine injected directly into your vein? While you might have a point, vaccines are not injected directly into the bloodstream.

Also, squalene is not in the "newest vaccine" in the US. Only in the EU, where it is approved for human use.

As for researching squalene and the immune response to it, you are correct. It's being done. As the link Abel Pharmboy posted said, which you probably should have clicked on: "More importantly, vaccination with a subunit influenza vaccine with the MF59 adjuvant neither induced antisqualene antibodies nor enhanced preexisting antisqualene antibody titers."


You can read more about this topic here:
http://www.sciencebasedmedicine.org/?p=1296
or here:
http://www.cdc.gov/vaccinesafety/Concer ... vants.html

/Scut
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