How can these doctors claim they are responders to beta interferon?
I suppose if one does worse on interferon, up until now, the finger of blame has not been pointed at interferon. People who did not respond to interferon have been called 'interferon-failures' whereas with this info perhaps some neuros will start to see interferon as an active agent in disimproving the disease course for some MS'ers, rather than the MS over-riding the interferons' supposedly positive effect - at least this study shows that in some people interferons are actually a negative effect on the disease course....well, in mice with EAE.
I know in my case, on interferon, I was considered 'worsening RR-MS' and my neuro wanted to give me chemo. Once I came off it and went on Copaxone I went back to just RR-MS. Interferon seemed to be 'upping' the number of relapses to 4 per year.
I'd be interested to know if high levels of IL-17F correlate to any types of MS, or specific types of disease course.
RR-MS dx 1998 and Coeliac dx 2003
Copaxone, Cymbalta. EPO, Fish Oils, Vitamin D3 2000 IU daily, Cal/Mag/Zinc, Multivitamin/mineral, Co-Enzyme Q10, Probiotics, Milk Thistle.