squiffy2 wrote:MS study suggests key role of environmental factor in the disease
Scientists are reporting what they say is compelling evidence that some powerful non-heritable, environmental factor likely plays a key role in the development of multiple sclerosis.................
http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1850
Yet scientists are unlikely to glean much immediate insight about MS from the work. One limitation, notes Geschwind, is that although Baranzini and colleagues examined epigenetics and gene expression in three twin pairs, they obtained the complete genome sequences of just one pair. "If we sequenced another dozen twin pairs we could make this much more definitive," says Kingsmore. And although the group targeted immune cells, "we really ought to look at sequencing of the brain tissue," he adds, as this might be an alternative site of genetic differences between the twins.
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