A good background:
http://www.roitt.com/elspdf/Autoimmune_ ... anisms.pdf
However, on the gene role, scientists study seem to be still focused on genes that regulate immunity assuming that issue starts there. In case of MS, studies are coming out that indicates that immune regulating genes aren't the culprit and issue could be due to gene defects that decide venous development. Just a thought ...
auto-immune diseases
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