Deaths overshadow ocrelizumab trials in MS

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Deaths overshadow ocrelizumab trials in MS

Postby MSUK » Thu May 20, 2010 10:08 pm

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Swiss drugmaker Roche AG and Biogen Idec Inc. are discontinuing development of ocrelizumab in patients with rheumatoid arthritis (RA), after an infection-related safety signal was observed in Phase III testing, resulting in the death of some patients.

Results from the program will be made... http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1397
MS-UK - http://www.ms-uk.org/
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Re: Deaths overshadow ocrelizumab trials in MS

Postby HarryZ » Fri May 21, 2010 6:54 am

squiffy2 wrote:Image

Swiss drugmaker Roche AG and Biogen Idec Inc. are discontinuing development of ocrelizumab in patients with rheumatoid arthritis (RA), after an infection-related safety signal was observed in Phase III testing, resulting in the death of some patients.

Results from the program will be made... http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1397


Monoclonal antibodies...powerful and dangerous drugs to say the least.

Interesting to see that they have abandoned the trials of ocrelizumab for RA but are continuing the trials for MS patients!

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