When helper cells aren't helpful

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When helper cells aren't helpful

Postby MSUK » Sun May 23, 2010 9:41 pm

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Current research suggests that T helper-type 1 (Th1) cells, previously thought to mediate autoimmunity, may actual inhibit the development of experimental immune encephalomyelitis (EAE), a mouse model of multiple sclerosis (MS), by suppressing Th17 cells.
The related report by Wildbaum et al, "Antigen-specific CD25-Foxp3-IFN-γ high CD4+ T cells restrain the development of experimental allergic encephalomyelitis by suppressing Th17 cells," appears in the June 2010 issue of The American Journal of Pathology........
[Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1100]
MS-UK - http://www.ms-uk.org/
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