Anyone tried Citicoline (CDP-Choline)

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Anyone tried Citicoline (CDP-Choline)

Postby Frank » Tue Jun 01, 2010 6:37 pm

Its available as a supplement and has neuroprotective and neurotrophic properties and is widely uses for ischemic stroke in Europe. It is said (after encouraging preliminary results there is a phase-III trial running now) that stroke patients treated with Citicoline have a better outcome regarding sustained disability.

In terms of MS I only found a patent from 2004 that combines Citicoline with steroids, but no published data on MS.

Has anyone tried it for MS? Any thoughts on that drug?

--Frank
Treatment: Gilenya since 01/2011, CCSVI both IJV ballooned 09/2010, Tysabri stopped after 24 Infusions and positive JCV antibody test, after LDN, ABX Wheldon Regime for 1 year.
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Re: Anyone tried Citicoline (CDP-Choline)

Postby ikulo » Sun Nov 27, 2011 9:29 am

Just wanted to bump this to see if anyone has had any experience with this yet.
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Re: Anyone tried Citicoline (CDP-Choline)

Postby NHE » Mon Nov 28, 2011 6:14 am

I have no experience with citicoline. However, here's a freely available review paper on it (although it is a few years old now).

http://ntp.neuroscience.wisc.edu/faculty/fac-art/adibhatla80.pdf

The paper's abstract states that citicoline is thought to increase the biosynthesis of phosphatidylcholine.

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Re: Anyone tried Citicoline (CDP-Choline)

Postby NHE » Mon Nov 28, 2011 7:07 am

Here are some additional papers from the same author.

CDP-choline Significantly Restores Phosphatidylcholine Levels by Differentially Affecting Phospholipase A2 and CTP: Phosphocholine Cytidylyltransferase after Stroke
http://ntp.neuroscience.wisc.edu/faculty/fac-art/adibhatla281.pdf

Cytidine 5 0 -Diphosphocholine (CDP-Choline)in Stroke and Other CNS Disorders.
http://ntp.neuroscience.wisc.edu/faculty/fac-art/adibhatla30.pdf

More papers from this author are available from the following link.
http://ntp.neuroscience.wisc.edu/faculty/adibhatla.html


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Re: Anyone tried Citicoline (CDP-Choline)

Postby ikulo » Wed Dec 07, 2011 10:00 pm

Thanks for the info, NHE! Will check that out.
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