Hi, Arron! Nice to "see" you too!
Sharon, Bromley and Harry..........how the heck are you folks doing?!
Sorry to have gotten off-track here a bit. As far as co-morbidity of depression and MS, I personally think that most physicians see something of a connection for more than just emotional reasons.
If you research what little they know about each medical condition physiologically, there are many similarities between the two (there is with bi-polar and schizophrenia, too). Having to do with glutamate, creatine, hormones (as Sharon mentioned), etc. etc. Even though depression itself isn't currently considered a "neurological" disease, in my opinion and speaking physiologically, it certainly could be. Trying to determine what came first sometimes is like the chicken and the egg. Did mild depression eventually escalate itself to causing a type of brain damage that over time could then be diagnosed as MS? Or did MS cause brain damage in parts of the brain that ends up causing depression? Could it be both?
Why is it that seriously depressed patients (who haven't been diagnosed with MS) have real (not imagined) physical trouble moving their bodies?? In many ways, researchers have described almost the exact same processes going on physiologically as what happens in the brain of MSers!
Now........on the other hand, depression does not always go hand-in-hand with MS. And CAN be just an "emotional" reaction to diagnosis and prognosis. The problem is, how can anyone tell the difference?
This again, though, leads me to believe there are different sub-types of MS. Take me for example. If I had stayed with one neuro, I would still be completely diagnosed and considered as having MS. Perhaps "benign" MS, but MS nonetheless. They would still be watching and waiting for it to eventually progress (and if asked now, they would probably say it WILL eventually progress. Slowly, but surely.) Actually, they could be correct. SOMETHING has progressed, because now the permanent neuro damage can be seen, but it has taken 30 years to get there.
Take fibromyalgia for example, too. Many MSers are diagnosed first as having fibro, and then over time, they are re-diagnosed as having MS. Some MSers will tell you that their physicians diagnosed them as having both. Coincidence? Or a connection? Some have fibro forever, but never get diagnosed with MS.
It's the "diagnosis" part of all this that is the "catch". Just because someone doesn't get "diagnosed" with MS, does that mean they really don't have it? Or it just doesn't quite fit the criteria (which changes all the time) for diagnosing MS................yet, that is?
Back to depression and MS. I am of the opinion that receiving treatment for depression is a good thing in any event, no matter how it arose. Medication used to treat depression does more to the body than just affect the one small portion of your brain that affects "mood". And indications are that many anti-depressants may indeed help the actual MS, too, even if it can't be completely proven...........yet.
No matter what is believed about depression, would it not be normal for anyone to experience sadness and/or emotional upset over any neurological disease diagnosis? (Not to mention frustration when dealing with the odd breed of physicians called "neurologists"..........