This Is MS Multiple Sclerosis Community: Knowledge & Support

Welcome to the world's leading forum on Multiple Sclerosis research, support, and knowledge. For over 10 years, This is MS has provided an unbiased community dedicated to Multiple Sclerosis patients, caregivers, and affected loved ones.
It is currently Thu May 23, 2013 12:54 pm


All times are UTC - 8 hours [ DST ]




Post new topic Reply to topic  [ 5 posts ] 
Author Message
PostPosted: Mon Jul 19, 2010 8:02 pm 
Offline
Family Elder
User avatar

Joined: Thu Jan 17, 2008 4:00 pm
Posts: 367
http://www.physorg.com/news198765070.html

"As we gained an appreciation for how profoundly the gut microbiota can affect the immune system, we decided to ask if symbiotic bacteria are the missing variable in these mice with MS," he says.

To find out, Mazmanian and his colleagues tried to induce MS in animals that were completely devoid of the microbes that normally inhabit the digestive system. "Lo and behold, these sterile animals did not get sick," he says.

Then the researchers decided to see what would happen if bacteria were reintroduced to the germ-free mice. But not just any bacteria. They inoculated mice with one specific organism, an unculturable bug from a group known as segmented filamentous bacteria. In prior studies, these bacteria had been shown to lead to intestinal inflammation and, more intriguingly, to induce in the gut the appearance of a particular immune-system cell known as Th17. Th17 cells are a type of T helper cell—cells that help activate and direct other immune system cells. Furthermore, Th17 cells induce the inflammatory cascade that leads to multiple sclerosis in animals.

"The question was, if this organism is inducing Th17 cells in the gut, will it be able to do so in the brain and central nervous system?" Mazmanian says. "Furthermore, with that one organism, can we restore to sterile animals the entire inflammatory response normally seen in animals with hundreds of species of gut bacteria?"

The answer? Yes on all counts. Giving the formerly germ-free mice a dose of one species of segmented filamentous bacteria induced Th17 not only in the gut but in the central nervous system and brain—and caused the formerly healthy mice to become ill with MS-like symptoms.


Top
 Profile  
 
 Post subject:
PostPosted: Tue Jul 20, 2010 12:22 am 
Offline
Family Member
User avatar

Joined: Sat Sep 24, 2005 3:00 pm
Posts: 32
I just found this article on my usual look through MS news on google - and just thought 'wonders will never cease' ..........
here I am - have been throwing up for 3/4 days and someone starts talking about the gut and MS.

Fortunately it seems to have calmed a little. I started on a probiotic 2 days ago. Hope it helps.....................


Top
 Profile  
 
PostPosted: Fri Jul 23, 2010 4:39 am 
Offline
Family Elder
User avatar

Joined: Wed May 24, 2006 3:00 pm
Posts: 284
Location: Near Wash DC
O.K.--- I have decided to rid my gut of ALL bacteria. I will take massive antibiotics to kill the bacterias and (correction - Valtrex 500 mg + Interferon Beta) to rid my self of ALL viruses. I will stop eating ALL fats and ALL proteins and ALL carbohydrates and ALL sugars and eliminate ALL SALT from my diet.

When I sober up I might modify a few of these statements a TAD.

jackD


Last edited by jackD on Fri Jul 23, 2010 7:24 am, edited 2 times in total.

Top
 Profile  
 
 Post subject:
PostPosted: Fri Jul 23, 2010 5:05 am 
Offline
Family Elder
User avatar

Joined: Sat Nov 21, 2009 4:00 pm
Posts: 782
Location: XinDian, Taiwan
Antibiotics will not get you rid of viruses.

You need fat to build myelin.

We need all; but in a balanced way.


Top
 Profile  
 
 Post subject:
PostPosted: Fri Jul 23, 2010 7:05 am 
Offline
Family Elder

Joined: Sun Aug 27, 2006 3:00 pm
Posts: 775
Location: Ireland
Quote:
O.K.--- I have decided to rid my gut of ALL bacteria. I will take massive antibiotics(correction - Valtrex 500 mg + Interferon Beta) to rid my self of ALL viruses. I will stop eating ALL fats and ALL proteins and ALL carbohydrates and ALL sugars.

When I sober up I might modify a few of these statements a TAD.

jackD


:lol: :lol: :lol: :lol: :lol: :lol: :lol: :lol: :lol: :lol: :lol:

_________________
~~~~~~~~~~~~~~~
Concussus Resurgo
~~~~~~~~~~~~~~~
RR-MS dx 1998 and Coeliac dx 2003
~~~~~~~~~~~~~~~
Copaxone, Cymbalta. EPO, Fish Oils, Vitamin D3 2000 IU daily, Cal/Mag/Zinc, Multivitamin/mineral, Co-Enzyme Q10, Probiotics, Milk Thistle.


Top
 Profile  
 
Display posts from previous:  Sort by  
Post new topic Reply to topic  [ 5 posts ] 

All times are UTC - 8 hours [ DST ]


Related topics
 Topics   Author   Replies   Views   Last post 
There are no new unread posts for this topic. Gut bacteria as a cause of autoimmunity in MS?

marcstck

1

1020

Wed Jun 14, 2006 11:05 am

beatms View the latest post

There are no new unread posts for this topic. RE BACTERIA ASSOCIATED WITHMS

seeva

2

921

Sat Oct 02, 2010 6:05 am

sbr487 View the latest post

There are no new unread posts for this topic. Simple description of bacteria

mscaregiver

0

1027

Tue Sep 28, 2004 8:44 pm

mscaregiver View the latest post

There are no new unread posts for this topic. Interesting "bacteria" story...

[ Go to pageGo to page: 1, 2 ]

Chris55

20

2362

Mon Sep 25, 2006 11:40 am

Chris55 View the latest post

There are no new unread posts for this topic. How bacteria can get into the nervous system

TwistedHelix

0

1352

Wed Aug 22, 2007 8:06 am

TwistedHelix View the latest post

 


Who is online

Users browsing this forum: curetoday


You cannot post new topics in this forum
You cannot reply to topics in this forum
You cannot edit your posts in this forum
You cannot delete your posts in this forum

Search for:
Jump to: