jerrygallow wrote:All those people who think they have gout and ms need to take a serious look at Lyme disease. Many docs don't understand Lyme and they stigmatize each other for diagnosing it because quacks say everything is Lyme. Plus there are no good tests for it. After a while the blood work looks normal. One study sent known samples to the labs and half the time the labs reported negative results though all samples were positive. Gout and ms almost never occur together while joint pain is a classic Lyme symptom
Multiple sclerosis and Uric acid levels
Lower serum values of uric acid have been associated with multiple sclerosis (MS). MS patients have been found to have serum levels ~194 µmol/L, with patients in relapse averaging ~160 µmol/L and patients in remission averaging ~230 µmol/L. Serum uric acid in healthy controls was ~290 µmol/L. Conversion factor: 1 mg/dL=59.48 µmol/L
A 1998 study completed a statistical analysis of 20 million patient records, comparing serum uric acid values in patients with gout and patients with multiple sclerosis. Almost no overlap between the groups was found.
Uric acid has been successfully used in the treatment and prevention of the animal (murine) model of MS.
A 2006 study found elevation of serum uric acid values in multiple sclerosis patients, by oral supplementation with Inosine, resulted in lower relapse rates, and no adverse effects.
Normalising low uric acid
Correcting low or deficient zinc levels can help elevate serum uric acid. Inosine can be used to elevate uric acid levels. Zn inhibits Cu absorption, helping to reduce the high Cu/Fe in some people with hypouricemia. Fe supplements can ensure adequate Fe reserves (ferritin above 25 ng/dl), also correcting the high Cu/Fe.