Do you take those combine at the same time? Do you take them year long or only when you have a relapse/symptome flare?
I have chronic pain, worse since procedure, I have tried all the neuroleptics, anti-depressors for pain Cymbalta, etc... I am on heavy dose of painkillers combine with patches, next step is 6days at the hospital to transfert to methadone. Research shown good results for pain control but I really really don't feel like it...
I tried Elavil 40 mg/d (with hydromorphe and dilaudid). Last time I have tried Lyrica - 150mg morning and night. Are those low dosage?
My next appointment is next week, I am willing to try anything before methadone. I am not even sure I will be allowed across the border if I take that!?!
Thank you for your help!
OBJECTIVE: To study the efficacy and safety of Super Malic, a proprietary tablet containing malic acid (200 mg) and magnesium (50 mg), in treatment of primary fibromyalgia syndrome (FM).
METHODS: Twenty-four sequential patients with primary FM were randomized to a fixed dose (3 tablets bid), placebo controlled, 4-week/course, pilot trial followed by a 6-month, open label, dose escalation (up to 6 tablets bid) trial. A 2-week, medication free, washout period was required before receiving treatment, between blinded courses, and again before starting open label treatment. The 3 primary outcome variables were measures of pain and tenderness but functional and psychological measures were also assessed.
RESULTS: No clear treatment effect attributable to Super Malic was seen in the blinded, fixed low dose trial. With dose escalation and a longer duration of treatment in the open label trial, significant reductions in the severity of all 3 primary pain/tenderness measures were obtained without limiting risks.
CONCLUSIONS: These data suggest that Super Malic is safe and may be beneficial in the treatment of patients with FM. Future placebo-controlled studies should utilize up to 6 tablets of Super Malic bid and continue therapy for at least 2 months.
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