Melody wrote:Also add turmeric 1/2 to 3/4 TBS per day. Both are anti-inflammatory and that could help.
Yes, there seems to be some good preliminary data that's been published on curcumin (an antioxidant derived from turmeric).
Curcumin inhibits experimental allergic encephalomyelitis by blocking IL-12 signaling through Janus kinase-STAT pathway in T lymphocytes.
J Immunol. 2002 Jun 15;168(12):6506-13
. Free pdf available.
Suppression of the nuclear factor-kappaB activation pathway by spice-derived phytochemicals: reasoning for seasoning.
Ann N Y Acad Sci. 2004 Dec;1030:434-41
By the way, I should note that epigallocatechin gallate (EGCG) from green tea and Lipoic Acid are also known to inhibit NF-kB.
Curcumin has also been shown to have possible benefit for Alzheimer's Disease...
Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo.
J Biol Chem. 2005 Feb 18;280(7):5892-901
Unfortunately, and in all fairness, I did find one paper which reported only marginal potential benefits for MS (or at least EAE)...
Oral flavonoids delay recovery from experimental autoimmune encephalomyelitis in SJL mice.
Biochem Pharmacol. 2005 Jul 15;70(2):220-8
...but then humans have been reported to be a poor model for the mouse immune system. I look forward to any study results with curcumin and MS patients. Any links to past or ongoing studies would be greatly appreciated. Thanks.