Can spinal lesions heal or rewire?

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Can spinal lesions heal or rewire?

Postby Tyr616 » Tue Nov 23, 2010 12:42 am

I know the brain can rewire around lesions with other synpases to "take over" function of the damaged brain area. But can this also happen for spinal lesions? Can the lesions in the spine heal, or have the signals restored and rewired like the brain?
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Postby tara97 » Tue Nov 23, 2010 5:54 pm

I had a very clear case of transverse myelitis and now there is no scar or evidence that it ever happened. The new neurologist doubted that It ever happened. luckily I kept the films from 6 years ago. I think that the peripheral nerves are repaired by shwann cells the nerves grow outward and reroute but I dont know what the spinal cord does.
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Postby goldamier » Tue Nov 23, 2010 8:39 pm

how long did it take for the scares to go away, i assume the systems went away as well right? :?:
thanks a lot for your help
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Postby tara97 » Thu Nov 25, 2010 6:46 pm

It remissed for 5 years and when it came out to play again the lesion was gone.
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Postby goldamier » Sat Nov 27, 2010 8:42 pm

thanks for getting back to me, if you don't mind one more question. If you don't mind, what was your symptoms, did you have electric shock upon bending your neck. The reason I am asking is that I have two lesions on my spinal cord and my symptoms have been attributed to them. It has been almost one year since the attack, and I want to know if I have any luck with the lesions to heal after this long time.
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Postby sou » Sun Nov 28, 2010 10:36 am

Let's be honest.

The long-term symptoms are not caused by the lesions. A more realistic approach would be the measurement of axonal density + spinal atrophy. The spinal cord has the ability of rewiring, just like the brain. The ability is not enough, though. Space, time and oxygen are required.

Space -> Spare neurons/new synapses
Time -> Intense training for a looooooong time in order to train the new randomly generated synapses
Oxygen -> Energy production. Our neuronal mitochondria are really in a bad shape, though. Not to mention about normal-for-the-skeptics CCSVI.

http://www.ncbi.nlm.nih.gov/pubmed/21061391
http://www.ncbi.nlm.nih.gov/pubmed/17950360

To make the long story short: The symptoms in MS are mostly caused by wider atrophy and not focal problems, such as lesions. The latter slightly contribute to symptoms, if any at all.

Expecting healing turns you immediately into a carrot following donkey. It is hard, very hard. But it is the truth. Whatever has happened has just happened.
Shortest joke: "We may not be able to cure MS but we can manage its symptoms."
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