Leonard wrote:This article postulates that bacteria in the sinus flora may be a factor in MS. In particular staphylococcal immune complexes are suspect.
http://www.sciencedirect.com/science/ar ... 4813000059
I do believe that the sinus infection is a factor in MS although it is not clear to me whether the sinus infection is causal or whether the infection is part of a bigger syndrome caused by weakened endothelial conditions in a bigger part of the head...
Leonard wrote:Terry Wahls writes in her book Minding My Mitochondria that "The health of our mitochondria affects the health of nearly every cell in the body. … Mitochondrial failure drives the development of diabetes, heart disease, lung disease, heartburn from stomach acidity, Alzheimer's, Parkinson's, many psychiatric disorders, and Multiple Sclerosis." …
I think this is true, very true. I think that mitochondrial stress and eventually failure underlies the progression for a majority of MS cases. Where an over-active immune system as is now being addressed by bone marrow transplantation (e.g. in Toronto, see another thread on this forum) is responsible only for a minority of MS cases. In addition, there are obviously the infectious agents, mainly responsible during the RR phase (see e.g. 1st posting page 1 on New Concept for MS).
The mitochondrial energy failure can be addressed by feces transplantation. In fact, and that point is also mentioned in the above article from the NYT but it is not further developed, the insulin sensitivity and the leptin sensitivity of all cells in the body can be greatly increased by feces transplantation. As the Amsterdam experiment shows ( http://www.cvgk.nl/legacy/bestanden/cvc ... rp-def.pdf ), even doubled in 6 weeks time. At the same time the permeability of the gut barrier will be reduced. As the NYT article elaborates and as can be found in the links below, the fat metabolism in the gut holds the key. (I guess Swank's low fat diet comes into the picture here as well).
If you do a Google search on mitochondrial energy failure insulin sensitivity leptin sensitivity you find many articles on how the gut microbiota influences the sensitivity of the cells.
http://www.plosbiology.org/article/info ... io.1001212
Our results emphasize the role of microbiota in the complex network of molecular and cellular interactions that link genotype to phenotype and have potential implications for common human disorders involving obesity, diabetes, and even other immunological disorders.
http://care.diabetesjournals.org/conten ... /2277.long
connect an altered microbiota composition to the development of obesity, insulin resistance, and diabetes in the host through several mechanisms: increased energy harvest from the diet, altered fatty acid metabolism and composition in adipose tissue and liver,..
http://bfg.oxfordjournals.org/content/e ... 4.abstract
The contribution of the gut microbiota to the development of several diseases (e.g. obesity, type 2 diabetes, steatosis, cardiovascular diseases and inflammatory bowel diseases)..
We conclude that specific gut microbiota modulation improves glucose homeostasis, leptin sensitivity, and target enteroendocrine cell activity in obese and diabetic mice. By profiling the gut microbiota, we identified a catalog of putative bacterial targets that may affect host metabolism in obesity and diabetes.
This paper presents an exhaustive review of the toxic effects of the herbicide, glyphosate, the active ingredient in Roundup®, in humans, and demonstrates how glyphosate's adverse effects on the gut microbiota, in conjunction with its established ability to inhibit the activity of cytochrome P450 enzymes, and its likely impairment of sulfate transport, can remarkably explain a great number of the diseases and conditions that are prevalent in the modern industrialized world. Its effects are insidious, because the long-term effects are often not immediately apparent. The pathologies to which glyphosate could plausibly contribute, through its known biosemiotic effects, include inflammatory bowel disease, obesity, depression, ADHD, autism, Alzheimer's disease, Parkinson's disease, ALS, multiple sclerosis, cancer, cachexia, infertility, and developmental malformations. Glyphosate works synergistically with other factors, such as insufficient sun exposure, dietary deficiencies in critical nutrients such as sulfur and zinc, and synergistic exposure to other xenobiotics whose detoxification is impaired by glyphosate. Given the known toxic effects of glyphosate reviewed here and the plausibility that they are negatively impacting health worldwide, it is imperative for more independent research to take place to validate the ideas presented here, and to take immediate action, if they are verified, to drastically curtail the use of glyphosate in agriculture. Glyphosate is likely to be pervasive in our food supply, and, contrary to being essentially nontoxic, it may in fact be the most biologically disruptive chemical in our environment.
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