One of my best friends has CRPS (RSD) and it has been awful to see this disease slow her down. She is in AGONIZING pain every single minute of every single day. She injured her heel in a race and developed into this. They diagnosed it after 6 months which was too late to give her the hope of remission. She has this for life. She honest-to-goodness would have her leg amputated because of the intensity of the pain, but the research shows that amputation actually makes the nerves fire even worse. She is on several different meds, but they don't touch the pain, but they help her sleep a little which, if she's lucky, is 3-4 hours a night. 5 if it's an especially good night. I just keep hoping that one day she'll wake up and everything will just disappear. Or that someone will figure out how to calm the nerves down. She has such a great attitude, though. Keeps smiling through the pain.
one very interesting comparison is RSD :http://www.canadianrsd.com/
Basically RSD is very intense nerve pain , bone pain and blood circulation issues... RSD develops after any soft tissue injury, it could be from an accident or from a disease... and it's like the immune system goes crazy trying to figure out how to deal with ths damn disease that will lead the infected body part to atrophy... this is exactly what happens to us with MS... MS causes brain atrophy (my guess is there must literally be some kind of "cancer" called MS that eat our brain collagen...), this leads to the RSD symptoms, where the immune system sends very painful signals (with aboslutely no result...)... The "good news" is that once the complete damage is done to the tissue, RSD stops, so once MS has eaten our brain, pain will stop....By the way, RSD causes also veins to spasm ( hallo, someone said MS causes CCSVI?...), but no matter how many interventions to open up blood vessels, it will not stop RSD (just like CCSVI "liberation" will not stop MS...) they are a consquence, not a cause...