Summary: This brief report from the authors represents the first published report of safety of natalizumab during pregnancy in women with multiple sclerosis. One patient used natalizumab in the periconceptional period, and the other patient used it in both the periconceptional period and throughout gestation.
The antenatal course of the first patient was complicated by an MS relapse. The second patient did not experience MS relapses during pregnancy, while still using natalizumab. Both babies were born without any detectable abnormality up to the sixth week of follow up.
Further data will be required before we can fully understand the safety implications of using natalizumab during pregnancy.... Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1936