Donepezil no help for memory deficits in MS

If it's on your mind and it has to do with multiple sclerosis in any way, post it here.

Donepezil no help for memory deficits in MS

Postby MSUK » Tue May 03, 2011 1:57 am

Image

The acetylcholinesterase inhibitor donepezil (Aricept) failed to improve multiple sclerosis patients' memory impairments in a placebo-controlled, multicenter trial, researchers said.

Neither patients' impressions of memory function nor their scores on an objective test of verbal memory -- the two primary outcome measures in the 120-person trial -- were better after 24 weeks of treatment with 10 mg/day of donepezil, reported Lauren Krupp, MD, of the State University of New York at Stony Brook.

The treatment also had no statistically significant benefits on secondary endpoints, although there was a trend favoring improvement in clinicians' impressions of change, she and her colleagues wrote in the April 26 issue of Neurology....Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1264
MS-UK - http://www.ms-uk.org/
User avatar
MSUK
Family Elder
 
Posts: 2156
Joined: Wed Oct 14, 2009 3:00 pm

Advertisement

Return to General Discussion

 


  • Related topics
    Replies
    Views
    Last post

Who is online

Users browsing this forum: No registered users


Contact us | Terms of Service