I did read the Coles abstract but unfortunately without the whole text of the article it doesn't really say a lot to me. I also watched the Giovanni presentation (In fact I nicked your link and posted it on another site because it does give a very good picture of the relevant benefits if the DMDs
). It is however somewhat out of date, I think it was from 2003; and as you know the picture of MS appears to change every two minutes let alone 2 years!
I completely agree that MS affects the grey matter, howver the loss of neurons can be attributed to the death of the connected axon due to transection or a toxic environment. I myself am still on the side of the inflammatory cause, particularly involving the microglia (remember the grey matter thread?
On a personal note I'm still doing very well, not long ago I walked a dog for over a mile without undue problems. 7 months ago the bottom of my garden was a bridge too far! I've gone from 4 relapses a year to Zero and counting
And my proudest achievement... I can stand on one leg without difficulty
Like you, I'm concerned about Rat. I really hope he was not the one unfortunate who died as a result of his treatment.
Whilst I don't post much anymore, I feel that I'm fundamentally biased these days; I do read your posts. Kudos for the amount of research that you do but please remember there is much more to life than MS. It's all too easy to let this disease dominate your life, I know, I've been there. If a cure comes then that's great, but while we wait there is so much life that we should be taking the time to enjoy. As the man said, carpe diem.
Hope you stay well.
Do not go gentle into that good night. Rage, rage against the dying of the light.