I hope you are sitting down when reading this because I just happen to agree with everything you just said
The CRABs are a cash cow to the pharmas who make them and like you said, they spend millions trying to prove their drug is better than the competition's. Open label, head-to-head trials....boy can you see what they can do to the stats that evolve from that!!
I found it interesting earlier this year when Tysabri started to get used in January and February. One reader (I believe it may have been on the Brain Talk MS Forum) compiled a number of comments made by several MS patients' neuros with respect to using Tysabri and stopping the CRABs. They stated that the CRABs were difficult to take, had several nasty side-effects, had very limited efficacy and were finally glad to rid their patients of them. Then bam...Tysabri got pulled and these same patients are back on the CRABs!