Found this on Parkinsons as well as brain damage
The DEA doesn't like it, but South Carolina psychiatrist Michael Mithoefer got FDA approval for the first double-blind study on the effect of MDMA on people suffering from post-traumatic stress disorder. Victims of violent crimes will get ecstasy combined with heavy therapy. The DEA has also touted research suggesting that MDMA causes Parkinson's disease, but a recent study out of the University of Manchester showed that the drug reduces tremors.
Print this page
Email to friend
Ecstasy Link To Long-Term Brain Damage
Disturbing evidence is emerging that the increasingly popular drug ecstasy can be linked to users suffering long-term brain damage.
Related News Stories
Ecstasy Component May Help Researchers Measure Brain Damage From The Drug (August 16, 2001) -- Researchers in Spain have isolated for the first time a by-product of the illicit drug Ecstasy that is believed to cause some of the brain damage associated with the drug. They believe their finding ... > full story
Ecstasy Affects Memory, New International Study Shows (January 15, 2004) -- People who take the recreational drug ecstasy risk impairing their memory, according to an international study which surveyed users in places including the USA, UK, other European countries and ... > full story
Reseachers Find Evidence That Prenatal Use Of Ecstasy Can Cause Long-Term Memory Loss And Other Impairments In Offspring (May 2, 2001) -- Researchers have reported the first evidence that a mother's use of MDMA (ecstasy) during pregnancy may result in specific types of long-term learning and memory impairments in her offspring. ... > full story
Hopkins Study Shows Brain Damage Evidence In "Ecstasy" Users (November 3, 1998) -- The common street drug "ecstasy" causes brain damage in people, according to a new Johns Hopkins study. In a report in The Lancet released last week, Hopkins scientists show that the drug -- ... > full story
> more related stories
Related sections: Health & Medicine
Mind & Brain
University of Adelaide researchers have found that ecstasy taken on a few occasions could cause severe damage to brain cells, with the potential to cause future memory loss or psychological problems.
Dr Rod Irvine, an internationally regarded ecstasy expert from the University's Department of Clinical and Experimental Pharmacology, says with 7% of 17-year-olds reporting use of ecstasy, major health problems could be expected in the future.
"For many years it has been known from animal experiments that small doses of ecstasy-even if only taken on only a few occasions-can cause severe damage to certain brain cells," he says. "More recently, evidence has started to accumulate suggesting that this damage may also occur in humans. Brain scans and psychological assessment of ecstasy users has been used to obtain this information.
"If our suspicions are proved correct, it will mean many of our young people will have memory loss or psychological problems in the future."
Dr Irvine's research on brain damage caused by ecstasy shows that the drug seems to work mainly through its effects on one type of brain cell, and even through one molecule in those cells. It also seems likely that the way the body reacts chemically to ecstasy is important in producing adverse effects, as is the surrounding temperature, which can lead to users overheating.
Adelaide's reputation as having the highest per capita death rate from ecstasy in Australia-and perhaps even the world-forms another component of Dr Irvine's research.
Dr Irvine is looking at the shorter-term consequences of ecstasy "overdoses", and has established that the high rate of death is due to a different strain of ecstasy appearing on the Adelaide market in the mid1990s.
"Normal" ecstasy contains the pharmacological ingredient known as MDMA as its main ingredient, but the Adelaide strain often contained no MDMA but rather a more potent chemical known as PMA.
"PMA hasn't been around since the early 1970s when it was responsible for the deaths of several people in Ontario, Canada, and now it's reappeared here in Adelaide," Dr Irvine says. "We don't know where the PMA came from, but we do know that it has been prevalent in Adelaide since the mid 1990s."