laetoli wrote:I think you are right that progress is being made in understanding the complexities of the human body at a cellular and molecular level. As these are better understood all diseases are benefitted. As regards MS, this is a painfully slow way of progressing.
What troubles me most is how little research goes into finding the cause of multiple sclerosis, which is something we still don't know around 150 years after the disease was first documented. A lot of people BELIEVE that the cause is autoimmunity (whatever that really means), others BELIEVE is is some kind of virus perhaps Epstein-Barr virus, others BELIEVE it is something to do with the flow of cerebrospinal fluid while still others BELIEVE it's a reaction between genes and the environment (like doh! but thus far genetic research hasn't revealed much w.r.t MS). These are just a few of the theories.
Let's not be in any doubt. They are just theories. None is backed up with hard data and until they are, they are no better than guesses.
What we need to see is research at the cellular level of the kind documented in this paper by Barnett & Prineas (http://www.CPn Help.org/files/Ref1_Annals04.pdf). A surprisingly small proportion of total MS research actually looks into how MS does its damage in human beings (for my money mouse models are a waste of time and resources because we know that the diseases are not MS). How can you cure or prevent a disease if you don't know what its cause is nor how it operates at the cellular and molecular level?
What I'd like to see is close to 100% of governments' and MS societies' sponsored research looking into the cause. Big (and little) pharma have no interest is the cause. They are companies and as such they need to see their profits maximised. They are looking for quickfire treatments. Because big pharma have much more money than MS Societies, they can be left to look for treatments while MS Societies look for a cause.
No cure without a cause.
As people with MS we should all be haranging MS Societies to spend more their research dollars on finding the cause.
laetoli wrote:What I'd like to see is close to 100% of governments' and MS societies' sponsored research looking into the cause.
Vikingquest wrote:Good points Paul, although I think it's pretty much solid fact that MS is an autoimmune disease, at least in the RRMS phase.
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