This Is MS Multiple Sclerosis Community: Knowledge & Support

Welcome to the world's leading forum on Multiple Sclerosis research, support, and knowledge. For over 10 years, This is MS has provided an unbiased community dedicated to Multiple Sclerosis patients, caregivers, and affected loved ones.
It is currently Wed May 22, 2013 6:00 am


All times are UTC - 8 hours [ DST ]




Post new topic Reply to topic  [ 6 posts ] 
Author Message
PostPosted: Thu Oct 27, 2011 12:27 am 
Offline
Family Elder
User avatar

Joined: Wed Oct 14, 2009 3:00 pm
Posts: 1686
Image

The spark that ignites multiple sclerosis may come from within. A new study in mice points to normal intestinal bacteria as a trigger for the immune disorder.

In patients with multiple sclerosis, the body’s immune system attacks the brain, stripping away a protective sheath called myelin from nerve cells. This causes inflammation that leads to the disease. Although the exact causes of MS are not known, scientists generally agree that a genetic predisposition combines with one or more environmental triggers to set off the attack on the brain. The new study provides evidence that friendly bacteria may be one of those triggers.

Mice genetically engineered to develop multiple sclerosis–like symptoms don’t get the disease when raised without any bacteria in their guts, a research team from Germany reports online October 26 in Nature. But germ-free mice that were then colonized with intestinal bacteria quickly developed the disease, the team found. About 80 percent of mice with intestinal bacteria developed MS-like symptoms, but none of the germ-free mice did.... Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/3021

_________________
The Multiple Sclerosis Resource Centre

Squiffy's House of Fun - Laughter for Multiple Sclerosis


Top
 Profile  
 
PostPosted: Thu Oct 27, 2011 1:41 pm 
Offline
Family Elder
User avatar

Joined: Fri Nov 13, 2009 4:00 pm
Posts: 194
this is the best article about the cause of MS, I just wonder when those reserchers will find how to kill these bacteria...


Top
 Profile  
 
PostPosted: Fri Oct 28, 2011 2:20 am 
Offline
Family Elder
User avatar

Joined: Fri Dec 18, 2009 4:00 pm
Posts: 479
Location: Brussels, Capital of Europe
Please read the last posting of 26 Oct on
general-discussion-f1/topic15188-225.html
The gut bacteria are mentioned there in the second to last paragraph as the cause of the second progressive phase.
I know it is all still a bit speculative at this point but the pieces seem to fit together so neatly..

And yes, I think it is known how these bacteria can be killed off by anti-biotics.
http://www.actrims.org/wp-content/uploa ... NAL_v2.pdf
This is from June 2010. See page 34

Or http://registration.akm.ch/einsicht.php ... N_ID=11599
See the third speech. This is from ECTRIMS/ACTRIMS Oct 2011.
Here minocycline comes into the puicture as well.
I have not seen any further details and would be very interested, if anyone can find.


Top
 Profile  
 
PostPosted: Mon Oct 31, 2011 8:02 pm 
Offline
Family Member
User avatar

Joined: Fri Jun 12, 2009 3:00 pm
Posts: 50
Something on the Microbiome
http://www.bbc.co.uk/news/magazine-15356016


Top
 Profile  
 
PostPosted: Fri Nov 04, 2011 4:09 am 
Offline
Family Elder
User avatar

Joined: Sat Dec 20, 2008 4:00 pm
Posts: 582
Location: Greece
I would consider it if I were a genetically modified mouse having an autoimmune disorder. I think this is not applicable to humans, though.

Yet another "give-me-funds" rubbish "MS research".

_________________
Shortest joke: "We may not be able to cure MS but we can manage its symptoms."


Top
 Profile  
 
PostPosted: Fri Nov 04, 2011 6:25 am 
Offline
Family Elder
User avatar

Joined: Tue May 25, 2004 3:00 pm
Posts: 2109
Location: London, ON, Canada
sou wrote:
I would consider it if I were a genetically modified mouse having an autoimmune disorder. I think this is not applicable to humans, though.

Yet another "give-me-funds" rubbish "MS research".


Have to agree with you Sou. Up to now, there hasn't been one successful treatment that worked on that poor MS mouse that ended up working on humans.

Harry


Top
 Profile  
 
Display posts from previous:  Sort by  
Post new topic Reply to topic  [ 6 posts ] 

All times are UTC - 8 hours [ DST ]


Related topics
 Topics   Author   Replies   Views   Last post 
There are no new unread posts for this topic. Low Serum Vitamin D Linked to Multiple Sclerosis

JFH

1

1083

Tue Feb 06, 2007 4:10 pm

jimmylegs View the latest post

There are no new unread posts for this topic. Ancient Virus Protein Linked to Multiple Sclerosis

OneEyeBlind

2

1255

Mon Oct 04, 2004 6:05 am

OneEyeBlind View the latest post

There are no new unread posts for this topic. Diabetes and Multiple Sclerosis Linked in Nationwide Danish

[ Go to pageGo to page: 1, 2 ]

Lyon

20

2892

Thu Jul 20, 2006 5:02 pm

Lyon View the latest post

There are no new unread posts for this topic. Multiple sclerosis drug linked to liver injury

missvicki

8

1988

Fri Feb 29, 2008 1:20 pm

trrish View the latest post

There are no new unread posts for this topic. Two Gene Locations Linked To Multiple Sclerosis Discovered

thinkingoutloud86

4

1190

Tue Jun 16, 2009 11:18 am

Sharon View the latest post

 


Who is online

Users browsing this forum: Loriyas


You cannot post new topics in this forum
You cannot reply to topics in this forum
You cannot edit your posts in this forum
You cannot delete your posts in this forum

Search for:
Jump to: