These disease models, which we already know create cortical inflammation and atrophy in vivo, need to be given the same millions of research dollars as the immunological focus. Why the NIH continues to fund immunological studies into MS, but refuses to fund mechanistic blood flow studies (such as the ones proposed by Dr. Cooke at Stanford and Dr. Haacke--who were both denied NIH money for the first times in their careers) astounds me.
marcstck wrote:It is unconscionable that the NIH would deny funding for bloodflow studies. The medical industrial complex is very real and very entrenched, and even though many who man it are people of good intent, the ghost in the machine folds, spindles, and mutilates…
cheerleader wrote:It's official. MS is no longer primarily an autoimmune disease of white matter. It's now an inflammatory disease of gray matter.
Press release from Mayo-
Research from Yale-
http://www.biomedcentral.com/content/pd ... 11-152.pdf
so, the EAE model and diagnosis will be changing, now that new, more powerful imaging technology is allowing researchers to see beyond white matter lesions, into the cortex.
Maybe they'll look at ischemic/reperfusion injury and iron deposition in gray matter next?
cheerleader wrote:rainer- I offer this thread as a memento of a kinder, gentler time--please note your comment, and mine.
(I miss Dom.)
how many more years? Jeff's doing well, thanks for asking.
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