Latent virus sparks inflammation in MS

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Latent virus sparks inflammation in MS

Postby MSUK » Wed Jan 04, 2012 12:41 am

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Epstein-Barr virus may play a role in multiple sclerosis (MS) by activating innate immune responses, researchers found.

Examination of postmortem brain tissue turned up RNA segments of the virus specifically in areas of active MS lesions overexpressing an inflammatory cytokine involved in innate immunity, according to a study by Ute C. Meier, DPhil, of Queen Mary University of London, and colleagues.

That cytokine, interferon-alpha, was overexpressed in active areas of white matter MS lesions but not in inactive lesions, normal-appearing white matter, or normal brain tissue from controls, the group reported online in Neurology.... Read More - http://www.msrc.co.uk/index.cfm/fuseact ... pageid/707
MS-UK - http://www.ms-uk.org/
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Re: Latent virus sparks inflammation in MS

Postby Leonard » Wed Jan 04, 2012 2:07 am

see also http://www.ncbi.nlm.nih.gov/pubmed/20593215

pages 17 (posting 27 Nov 3:50) and 18 place things in a broader context general-discussion-f1/topic15188-240.html
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