Inflammation is the body's response to something e.g. if you cut your finger it becomes inflammed as the immune system targets any foreign invaders
I don't think anyone disputes that there is a trigger that starts the inflammatory process in MS. That trigger may well be an infection but why is it so hard to believe that the immune response gets out of control? All of the proposed pathogens EBV, CPn etc. are endemic yet virtually harmless in 99.9% of the human population. There is something in our genetic makeup that makes us susceptible to something more serious.
We've all seen those fantastic displays where they line up thousands of dominoes, kick over the first one and the others follow. Remove just one of those dominoes and the process halts. Righting the first one after it has started the process has no effect.
The trick is removing a domino that can halt the effect without causing a problem elsewhere as in Tysabri and PML.
Another analogy: Smoking causes lung cancer. It is however not the only cause. You can develop lung cancer without ever having smoked or having been exposed to cigarette smoke. If you develop lung cancer then stopping smoking is not going to help. The cascade of events has already taken over.
With MS clearing the triggering infection may not stop the deterioration.
All of the observed facts of MS including the grey matter deterioration, the failure of Campath and AHSCT to halt progression in the later stages and the subtypes of the disease can be adequately explained under the current auto-immune model.
If there is another model that can explain all of this then I would be interested to hear it, but I haven't found one.
MS and the whole immune system is a bloody complex problem. Just because they haven't got a cure yet does not mean that they are looking in the wrong place.
Take nuclear fusion, the holy grail of the energy world. We know the how's and the why's. You can create fusion on a desktop fairly easily if you build a Farnsworth fusor. However, generating energy in usable quantities without blowing the crap out of ourselves in the process remains a distant dream.
Give it time, the answers will come. Until then there is life there to be enjoyed. Don't let MS take more of your life than it absolutely has to.
p.s. See ya Wednesday
Do not go gentle into that good night. Rage, rage against the dying of the light.