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Effect of vitamin D3 supplementation on relapses, disease progression and measures of function in persons with MS



Exploratory outcomes from a double-blind randomised controlled trial.

Summary: The authors report data from a 96-week randomised controlled treatment trial of vitamin D(3) supplementation on annualised relapse rate (ARR), EDSS, multiple sclerosis functional composite (MSFC) components, grip strength, and fatigue.

In patients with multiple sclerosis supplemented with 20,000 IU vitamin D(3) weekly there was no significant difference in ARR, EDSS, MSFC components, grip strength, or fatigue. Although the study was not powered to address clinical outcomes, none of the results were suggestive of a clinically meaningful effect of vitamin D(3) in this unselected population of fully ambulatory persons with multiple sclerosis.... Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1334

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