Dr. Zivadinov asks, is it time to redefine MS pathogenesis?

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Re: Dr. Zivadinov asks, is it time to redefine MS pathogenes

Postby cheerleader » Fri Mar 22, 2013 7:32 pm

yeah...well, BNAC is getting $ for four studies on how the current drugs affect gray matter.
So, you were right, Harry. Pharma isn't giving up on their investment.
I was hopeful this would help CCSVI research, but there's just no money in that.

1. A prospective, observational, single-blinded, longitudinal study of atalizumab effect on brain atrophy and disability in multiple sclerosis patients over 5 years. Agency: Biogen Idec, Inc.

2. Evolution of gray matter (GM) atrophy over 4 years in observational study of early interferon (IFN)β-1a intramuscular (I.M.) (Avonex® ) treatment in high risk subjects after clinically isolated syndrome (SET substudy). Agency: Biogen Idec, Inc.

3. Assessment of lesion activity analysis in the Avonex- Steroid-Azathioprine (ASA) study.
Agency: Biogen Idec, Inc.
Aim: To examine short- and long-term value of appearance of new active lesions in predicting extent of cortical and subcortical atrophy over 5 years in ASA study.


and Teva is looking at if GA affects iron deposition in deep GM.

4. A prospective, observational, single-blinded, longitudinal MRI study of effect of glatiramer acetate on iron deposition in patients with relapsing-remitting multiple sclerosis over 24 months.
Agency: Teva Pharmaceuticals, Inc.
Aim: To explore whether treatment with GA may decrease iron deposition in subcortical deep GM, as detected by SWI-filtered phase imaging, in patients with RRMS over 24 months and compared to a reference population of healthy controls. To investigate whether treatment with GA may decrease accumulation of iron in lesions, as detected by SWI-filtered phase imaging, in patients with RRMS over 24 months.

http://www.bnac.net/?page_id=359

sigh,
cheer
Husband dx RRMS 3/07
dx dual jugular vein stenosis (CCSVI) 4/09
http://ccsviinms.blogspot.com
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