Scientists pinpoint antibody that may be specific to MS

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Scientists pinpoint antibody that may be specific to MS

Postby MSUK » Thu Jul 12, 2012 1:47 am

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Researchers have identified an antibody found in the blood of about half of patients with multiple sclerosis that is not found in people without the autoimmune disease.
The implications of the antibody's presence aren't fully understood. But in rodents, the antibody binds to and damages brain cells that are known to be important to neurological function, according to the study.

Although the research is preliminary, experts say the findings may open the door for a blood test that could more easily diagnosis multiple sclerosis (MS) patients. The results also suggest a new target for MS treatments that would prevent the antibody from binding to brain cells.

"We have known for a long time that antibodies were involved in the destruction of nervous system tissue in MS, but we have not had a good handle on what the target was for these antibodies," said Timothy Coetzee, chief research officer for the National Multiple Sclerosis Society, who was not involved in the study. "What this research has identified is what might be a potential trigger or target in MS."

The study is published in the July 12 issue of the New England Journal of Medicine.... Read More - http://www.msrc.co.uk/index.cfm/fuseact ... geid/1100/
MS-UK - http://www.ms-uk.org/
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