To date much of the focus of MS research has been in relation to T cells. Several research papers have pointed to B cells as having an involvement in the pathogenesis of MS and perhaps in terms of axonal damage. I have previously posted on the drug Rituximab which depletes B cells and has shown promising results. This drug is being tested in RR, SP and PP MS.
The NMSS is funding research in relation to B cells. One grant has gone to Dr Monson. Attached is a link to Dr Monson's work. It's a bit techy but it's good to know that there are researchers beavering away in this promising area.