This Is MS Multiple Sclerosis Community: Knowledge & Support

This one is for Sharon.

http://www.timesonline.co.uk/article/0, ... 06,00.html

Thanks Bromley— The article states:

I must say from my reading about hormones I am of the impression testosterone may reduce the susceptibility of being diagnosed with MS and estrogen definitely seems to be anti-inflammatory. I don’t know anything though about the innate/adaptive immune systems and have no earthly idea why the adaptive immune response in women would make them more susceptible to auto-immune diseases. I’m curious to learn from the auto-immune experts why that would be the case. It’s going to take a lot to convince me that MS is auto-immune.

That estrogen is anti-inflammatory and neurprotective is reviewed in part in this abstract, From clinical evidence to molecular mechanisms underlying neuroprotection afforded by estrogens . Another abstract highlights the role of mitochondria in neuroprotection afforded by estrogen. Mitochondria play a central role in estrogen-induced neuroprotection Note:

Mitochondrial dysfunction, as already posted elsewhere, may be real relevant to MS too. Mitochondrial Dysfunction as a Cause of Axonal Degeneration MS

Enough about estrogen. One of these days Bromley I’ll have a post that says “This One’s For You”…..I really do appreciate your posting info you think I’d be interested in. I am.

Sharon