This Is MS Multiple Sclerosis Community: Knowledge & Support

Just wondering if anyone else has ovoid plaques in this area? I've had 2 MRI's within the last year that shows ovoid plaques in/on left and right frontal lobes with minimal demyelination and the radiologist's last impression says to correlate for possible MS. Well, I've been to 2 neuros within the last 9 months and neither one wants to further investigate, or even talk about, these findings or my symptoms. From my own research, I know this is not a "normal" area for MS lesions but, I have read where people have been dx with MS in this area. It's been 7 years since my symptoms started and this past year, things seem to be getting worse!

I have lesions in my frontal lobes:( I have MS but they look like demyelination (as far as I know)

How long did it take you to get a dx? Did you go through the doubtful neuros because of where they're at?

It took me years to get a diagnosis but that's because my MRI's were clean. In the last 3 years I have 2 very large frontal lobe,lesions as well as lots of lesions in other parts,of the brain. They do say typical of demylination though on reports

I'm waiting to actually go to an MS Clinic on Feb 19th (can't come soon enough for me)! Hopefully I'll finally get some definate answers.

For 14 years my MRI's were clean and had 2 negative lp's.
In 09 I had a big relapse and my MRI on my brain showed lesions and so did my spine my lp also became positive.
For years the Dr's told me nothing was wrong even though my aunt had ms.

I hope u get some answers soon and that its not ms but something curable or easily treatable x

Thank you so much! I went 5 yrs before anything showed in my frontal lobes. Then a year later, it was the same exact findings...no changes. I've had numerous blood tests, lp, t-spine mri, ver, baer, xrays, etc and all of that has been negative. By any chance, do you have nystagmus?

Wow you have been through a lot.

Yes I had a bad attack of vertigo a couple of years ago thankfully my balance is back to normal but a year before the vertigo hit I started having issues when trying to read labels arkets, I noticed my eyes were jerking around. During the vertigo though it was so severe. Again thankfully it is very mild again now. Although I have had a recent optic neuritis attack but that affected the vision rather than nystag
How big/numerous are your frontal lobe lesions? Have you had any cognitive issues because of them? X

I've never had ON. Everything started with me back in June '05....while on a road trip, my eyes started feeling like they were jerking and swirling, which caused me to be very "dizzy" feeling. These episodes would last a few weeks then just go away and come back every few months. But, this most recent episode has been going on for about 6 months now...it just comes and goes throughout the day. I haven't noticed anything that is triggering it either. It happens whether I'm doing something or nothing at all. It is extremely hard to drive with it though! When it happens, I do lose my focus for a few seconds.

Then in Sep- Oct '05...all my other symptoms just hit me, all at once...pain, numbness, weakness, jerks, fatigue, anxiety, etc so dr thought MS and did MRI which showed nothing so she sent me to a rheuma which dx me with fibro. I've had all of these symptoms off and on throughout the years. They seem to never go away, every day it's always one symptom or another.

Then Nov '11 went to different dr and she thought either seizures or MS from all my symptoms I described to her...EEG was normal but that's when the ovoid plaques showed in both frontal lobes on MRI. She sent me to neuro which kept telling me they were due to headaches, which I kept trying to tell her I rarely get! Then dr sent me to another neuro after having another MRI done in Oct '12 which showed the same thing and radiologist impression said to correlate for possible MS(same radiologist that read the other one). First this neuro started with the headache thing and I told him that's why my dr sent me to him because that's what the last one said! So then he said, well I can't say it's not MS but at this point I feel it's fibro and CFS.

Neither of these neuros are MS specialists. So my dr got mad that neither is listening or addressing the findings and that's why she's referred me to the MS Clinic.

To answer your question...I do suffer with cognitive issues...severely! I hardly have any memory of my past, I forget things all the time, do stupid things like lighting a cig when I've just lit one or try to put my lighter in the ashtry instead of the cig, get lost sometimes...took me 3 times missing a turn, to get my son to dr a few weeks ago, and I always feel like I'm outside looking through a window at my life (if that makes sense) it's like I'm there and I know I'm there, but I'm not (like I'm in a bubble or up on a cloud)...just a feeling that is hard to describe. Someone, my husband for instance, will be talking to me and asking me a question and I'll hear him talking but it's like a delayed response for my answer after I ask him again what he said. And sometimes I'll mix the first letter of words up when talking like...Is the loor docked? Instead of Is the door locked?...crazy and frustrating!

Also, I don't know how many or how big the lesions are...it just says ovoid plaques in/on both left and right frontal lobes with minimal demyelination and something about periventricular.

What type of MS do you have? Is it tumefactive? It seems about everything I've read that deals with frontal lobe lesions points to that.

I have relapsing remitting MS.

I know exactly what you are talking about when you are there but not there. You hear what people are saying and you respond but somehow you don't feel connected. Its not a dream state but rather like you are not fully whole and plugged in.

When I first got the lesions in the frontal lobes it was so bad, I had that feeling all the time and I had no motivation to do anything, I also lost the desire to talk (it was weird I could talk, just didn't feel like talking!) but if its any consolation, your brain can heal or at the very least re-route, mine has as I feel like me again. Also I had another problem where I had no feelings of emotion, it was like someone had taken away my ability to get enjoyment, I was flat. I didn't even want a cuddle off my dogs, I didn't have that connection with them or my family....very wierd . Again thankfully my brain has sorted that out.

There are a couple of good websites I started using to get my brain working again (Posit science &Thetamusic). I recommend you joining at least the music one as there are so many free games and even if you are not musical it really gets your brain working.

Can I suggest you get your blood coagulation looked at as well as your thyroid....my thyroid has always been a problem and I have thick/sticky plus always have high levels of fibrinogen which I am sure is contributing.

Wow, that's how I am....I have no motivation...all I want to do is sleep. It seems like the littlest chore just wears me out and I have to lay down and go to sleep. I've come to the point where I'm not wanting to talk to anyone too and, I HATE going anywhere. My life revolves around sleep...I go to bed at 8, get up thinking can't wait until 8 to go to bed and everything I do or need to do or want to do, I'm always thinking...I can't do that because it will interrupt my nap!

I've noticed I've become flat. Nothing really seems funny to me. And my voice has become one tone, not really much low or high pitch.

I'll check those sites out, I love to play games (words with friends and any type of solitaire and mahjong) although with my eye problem, I've had a hard time lately. How does your brain retrain? and heal? Is it going to take MS meds to do this?

My thyroid has been check a few times by different drs throughout the years but, I don't recall any of them saying anything about checking my blood coagulation. I do know all about that though because my husband has a blood clotting disorder and is on coumadin for life. And, now that I think about it, my brother found out last year that he has a blood disorder so maybe that is a good idea.

Thank you so much for responding, you have been so helpful and kind!

My MRIs say that there are several lesions (no actual number) but that there are 2 large ones in the left frontal lobe! I have gotten nowhere with a general neurologist (never actually saw him, just his NP) so I am scheduled to see an MS specialist on February 5th. Praying for some answers soon!!!

Maybe lesions in the frontal lobe are not that uncommon with MS. Please keep us updated with what happens with you guys.

@Ikae, no worries anytime you want to chat feel free to PM me x

Hope you get some answers, good luck with your appt and plz keep us posted.