This Is MS Multiple Sclerosis Community: Knowledge & Support

Welcome to the world's leading forum on Multiple Sclerosis research, support, and knowledge. For over 10 years, This is MS has provided an unbiased community dedicated to Multiple Sclerosis patients, caregivers, and affected loved ones.
It is currently Mon May 20, 2013 6:03 pm


All times are UTC - 8 hours [ DST ]




Post new topic Reply to topic  [ 6 posts ] 
Author Message
 Post subject: Dr Calabresi webcast
PostPosted: Mon Mar 13, 2006 10:12 am 
Offline
Family Elder
User avatar

Joined: Fri Sep 10, 2004 3:00 pm
Posts: 1889
The NMSS has a webcast today (as part of MS week) featuring Dr Calabresi - 'Repair of MS damage and Protection of the Nervous System'.

Attached is the transcript.

Not too much new stuff but it looks like they are looking at existing drugs which should speed up the work.

Ian


http://skins.broadbandvideo.com/nmss2/2 ... script.pdf


Top
 Profile  
 
 Post subject:
PostPosted: Mon Mar 13, 2006 7:20 pm 
Offline
Family Elder
User avatar

Joined: Sat Feb 18, 2006 4:00 pm
Posts: 516
Location: suburb of Chicago, IL USA
Wow this is exciting to hear. It would be great if they can repair the myelin and give us more time for them to find a cure. I'm assuming that if they use already FDA approved medication that all they will have to prove is effectiveness so the trial should be shorter- or am I just wishful thinking? It was nice to hear a top researcher state confidently that this is going to happen because sometimes I think I am delusional for being so optimistic. Does anyone know if it is believed that older plaques may be able to be remyelinated or is it just newer ones that still have partial remyelination occuring? Also, how about axons that have already been damaged? Either way, great news!!


Top
 Profile  
 
 Post subject:
PostPosted: Mon Mar 13, 2006 8:53 pm 
Offline
Family Elder
User avatar

Joined: Fri Feb 06, 2004 4:00 pm
Posts: 750
Scoobyjude--

You asked:
Quote:
Does anyone know if it is believed that older plaques may be able to be remyelinated or is it just newer ones that still have partial remyelination occuring? Also, how about axons that have already been damaged?


Here's something on the topic which seems to suggest remyelination is possible. I don't know though if it's in "older plaques".
CNS Axons Retain their Competence for Myelination Throughout Life
Quote:
there are no changes in axons remaining unmyelinated for many months that would prevent effective remyelination. This finding suggests that chronically demyelinated regions of axons such as those in seen in multiple sclerosis are likely to remain competent to be remyelinated.


I have no idea about repairing axons.

Sharon


Last edited by Shayk on Mon Mar 13, 2006 9:23 pm, edited 1 time in total.

Top
 Profile  
 
 Post subject:
PostPosted: Mon Mar 13, 2006 9:11 pm 
Offline
Family Elder
User avatar

Joined: Sat Feb 18, 2006 4:00 pm
Posts: 516
Location: suburb of Chicago, IL USA
Who knows Sharon, they may play a part yet. If that is what you believe then who am I or anyone else to tell you differently. You have done a lot or research that supports your theory and I have to say it makes a lot of sense. I've always thought that the fact that pregnant women suffer less relapses shows that hormones affect MS. Whatever keeps you going I say. I was asking about older plaques in regards to those with SPMS and those who have had MS longer. My plaques are pretty new so I hope that they will be able to be remyelinated. I hope that this will be a promising treatments for all types of MS.


Top
 Profile  
 
 Post subject:
PostPosted: Mon Mar 13, 2006 9:25 pm 
Offline
Family Elder
User avatar

Joined: Fri Feb 06, 2004 4:00 pm
Posts: 750
Hi again Scoobyjude--

I just deleted the part about "axotomy". It really pertained to saving motoneurons and not axons. Sorry about that and I regret the information I shared didn't address your question either.

Sharon


Top
 Profile  
 
 Post subject:
PostPosted: Tue Mar 14, 2006 10:30 pm 
Offline
Family Elder
User avatar

Joined: Sat Feb 18, 2006 4:00 pm
Posts: 516
Location: suburb of Chicago, IL USA
Sharon, actually what you posted did pertain to my question. From what I read it seems that even chronically demyelinated axons and I'm assuming plaques still have the ability to be remyelinated. Although, I could be wrong because I am not very scientifically inclined. That's why I need all of you to read the articles and tell me what they mean :D


Top
 Profile  
 
Display posts from previous:  Sort by  
Post new topic Reply to topic  [ 6 posts ] 

All times are UTC - 8 hours [ DST ]


Related topics
 Topics   Author   Replies   Views   Last post 
There are no new unread posts for this topic. Dr Steinman webcast

bromley

4

1088

Fri Mar 17, 2006 1:48 pm

bromley View the latest post

There are no new unread posts for this topic. Preventing Multiple Sclerosis webcast

Nick

5

1463

Tue May 03, 2005 7:42 am

OneEyeBlind View the latest post

There are no new unread posts for this topic. Upcoming Webcast on Nervous System Repair

patientx

5

963

Sun Dec 26, 2010 4:29 pm

Brainteaser View the latest post

 


Who is online

Users browsing this forum: No registered users


You cannot post new topics in this forum
You cannot reply to topics in this forum
You cannot edit your posts in this forum
You cannot delete your posts in this forum

Search for:
Jump to: