Welcome to ThisIsMS, Jules.
Every case of MS seems to have a unique collection of symptoms. And every member here has his own unique ideas about the disease. MY suspicion centers around excess insulin, which causes insulin resistance in the smooth and skeletal muscles.
I suspect you have difficulty sitting up straight at your desk because your core muscles are affected and weakened by excess insulin (insulin resistance), I encourage you to ask your GP to order a "fasting blood insulin test." (With your mention of "Scotland" you may be interested in the following BCG info.)
I am on the mailing list of Dr. Denise Faustman, a Harvard University researcher working on a cure for type I diabetes. She has triggered increased insulin production from trial participants with previously non-producing pancreas. In her fall letter were links giving more information on her work: http://www.myfoxboston.com/story/192352 ... t-diabetes
Here is a Bloomberg article with more details: http://www.bloomberg.com/news/2012-08-0 ... or-tb.html
Dr. Faustman is also doing research on MS and thinks the BCG vaccine will help, but I do not agree – because of a friend's experience. My friend grew up in Ireland where she moved around often and attended several schools; a BCG vaccine was required at each new school (the BCG vaccine is required of school-age children in the UK)– she thinks she has received the BCG vaccine four times. She now has MS.
I think the increased insulin Dr. Faustman has found to be triggered by the BCG vaccine will make MS worse. This vaccine uses attenuated (weakened), i.e., live bacteria. Is it possible that BCG (bacillus Calmette-Guérin) continues to live in the body and is NOT eliminated by antibodies, OR that the bacterium changed the pancreas into chronically overproducing insulin? I think this BCG vaccine could be responsible for many cases of MS because it increases insulin production.
My hypothesis: excess insulin (hyperinsulinemia) plays a major role in MS, as developed in my initial post: http://www.thisisms.com/forum/general-discussion-f1/topic1878.html "Insulin – Could This Be the Key?"