ranbar wrote:It was suggested I go on Tysabri, but I am concerned about the lethal side effects. I didn't realize it helped with mobility, and other symptoms. Doesn't it have a 2 year use limit, for best results? What then?
tysabri doesn't have a use limit, but increased length of use increases the risk of pml.
One big consideration is to get a serum JC virus ELISA to stratify risk of pml. You may want to ask for this blood test.
Another factor is whether or not you have previously been on immunosuppressants (azathioprine, cyclospirine, cyclophosphamide, methotrexate, etc.)
Here are the statistics:
campath and gilenya also have side effects.
campath: risk of various infections, autoimmune thyroiditis
gilenya: first dose decreased heart rate/sudden cardiac death, macular edema, pulmonary/liver/heart issues.